Duramune® Puppy DP+C is a combination vaccine presented as a lyophilisate and solvent for suspension for injection. Each dose comprises one vial of a freeze dried fraction containing live attenuated strains of canine distemper virus, strain Onderstepoort, (102.5 to 104.8TCID50); and canine parvovirus, strain SAH (104.7 to 106.5TCID50) and one vial of liquid diluent fraction, an inactivated suspension of canine coronavirus, strain TN449 (RP of 1.0-2.0).