For Animal treatment only

Do not use in horses intended for human consumption.

Do not use with sympathomimetic amines.

Do not use in the last month of pregnancy.

Do not use with potentiated sulphonamide drugs.

Do not mix with other products.

Do not use in horses with pre-existing AV blocks, with severe coronary insufficiency, respiratory disease or chronic renal failure. Careful consideration should be given to administration to animals in shock and to animals with liver or kidney disease.

Do not offer food or water until drug effect has passed.

Give by slow intravenous injection only.

Administration of Equimidine may cause benign, reversible cardiac arrhythmia, in-coordination of the limbs and sweating. Slight tremor of individual muscles or muscle groups may occasionally be observed. An diuretic effect is usually observed within 45 to 60 minutes of treatment.

Equimidine should be used with care with other sedatives and anaesthetics because of an additive/synergistic effect.

Equimidine with butorphanol for sedation: Do not use this combination in horses intended for human consumption or in horses with a history of liver disease. This combination should not be used in pregnant mares or in animals suffering from colic. Routine cardiac auscultation should be used prior to use of this combination. Do not use in horses with pre-existing cardiac dysrhythmia or bradycardia. Mild to severe ataxia may be encountered but clinical studies have shown that horses are unlikely to collapse. Normal precautions should be taken to prevent patient self injury.

Equimidine with ketamine (short duration anaesthesia): Allow sedation to develop for at least 5 minutes before giving ketamine. The two agents should never be co-administered in the same syringe. It is recommended that feed is withdrawn for at least 12 hours prior to anaesthesia. Excitable horses can be poor subjects for anaesthesia. Considerate, quiet and careful handling during the administration of agents is necessary to cause the minimum upset possible. If sedation with Equimidine fails to occur then the procedure should be abandoned. In these circumstances ketamine must not be injected into the horse.

Operator Warnings: Care should be taken to avoid accidental self-injection. In case of accidental self administration, seek medical advice immediately and show package insert or label to the physician. DO NOT DRIVE as changes in blood pressure may be seen. Wear protective rubber gloves when using this product. Wash off splashes from skin or eyes.