FOR ANIMAL TREATMENT ONLY

Ketaset is metabolised by the liver and excreted via the kidney and hence should not be used in animals with hepatic or renal failure.

A small proportion of animals has been reported to be unresponsive to Ketaset as an anaesthetic agent at normal doses.

Care should be taken when using Ketaset-halothane combinations, since the half-life of ketamine is prolonged.

Xylazine should not be used in the latter stages of pregnancy. Medetomidine is not recommended in pregnant animals. Use of premedicants should be followed by a suitable reduction in Ketaset dosage. In the dog, the eyes remain open and pupils dilated. The eyes may be protected by covering with a damp gauze swab.

Consult the contra-indications that appear on the Torbugesic Injection and Domitor data sheets. There may be some pain on intramuscular injection.

Xylazine should not be used in the latter stages of pregnancy. Medetomidine is not recommended in pregnant cats. Use of premedicants should be followed by a suitable reduction in Ketaset dosage. Ketaset may cause salivation in cats. Atropine premedication may reduce this side affect. Muscular twitching and mild tonic convulsions have been recorded in the cat at recommended dose rates. These subside spontaneously but may be prevented by use of acepromazine or xylazine premedication, or controlled by use of acepromazine or ultra short-acting barbiturates in low doses. In the cat, the eyes remain open and pupils dilated. The eyes may be protected by covering with a damp gauze swab.

Consult the contra-indications that appear on the Torbugesic Injection and Domitor data sheets. There may be some pain on intramuscular injection.

Do not use Ketaset as a sole agent in the horse. Xylazine should not be used in the latter stages of pregnancy. Detomidine should not be used in the last month of pregnancy. Romifidine should not be used in the last month of pregnancy. Not to be used in animals intended for human consumption. Treated horses must never be slaughtered for human consumption. The horse must have been declared as not intended for human consumption under national horse passport legislation.

In some horses, a mild, reversible heart block has been observed following premedication with detomidine.

Overdosage: If necessary, suitable artificial aids to maintain ventilation and cardiac output should be used until sufficient detoxification has taken place to enable a return to adequate spontaneous ventilation and cardiac activity. Pharmacological cardiac stimulants are not recommended, unless no other supportive measures are available.