After the final milking of a lactation, clean and disinfect the teats and introduce the contents of one tube into each quarter via the teat canal.

When infusing heifers it is important that the syringe nozzle is not introduced into the teat. The recommended procedure for dosing is as follows: The teats are cleaned and disinfected. The teat orifice is located and the nozzle of the syringe placed against it but not inserted. When the syringe plunger is depressed the antibiotic passes easily through the teat into the udder.