Resistance to many antibiotics is caused by beta-lactamase enzymes, which destroy the antibiotic before it can act on the bacteria themselves. The clavulanate in Nisamox Tablets counteracts this defence mechanism by inactivating the beta-lactamases, thus rendering the organisms sensitive to amoxicillin’s rapid bactericidal effect, at concentrations readily attainable in the body. Inappropriate use of the product may increase the prevalence of bacteria resistance to amoxicillin/clavulanic acid.