Introduction

Company name: Fort Dodge Animal Health

Address: Flanders Road

Hedge End

Southampton SO30 4QH

Telephone: 01489 781711

Fax: 01489 788306

Presentation

White circular uncoated tablets scored on one side.

Each tablet contains

Trimethoprim Ph.Eur	80 mg
Sulfadiazine Ph.Eur	400 mg

Uses

Duphatrim 80 Tablets are indicated for oral use in dogs. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria, resulting in a level of activity much greater than that obtained from either drug alone. In vitro Duphatrim is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Pasteurella multocida, Streptococcus spp, Staphylococcus spp, Salmonella spp, Corynebacterium spp, Proteus mirabilis and Citrobacter freundii.

When susceptible organisms are present Duphatrim 80 Tablets may be effective in treating the following conditions:

• Alimentary tract infections.

• Respiratory and urogenital infections.

• Skin and wound infections.

• Eye and ear infections.

Dosage and administration

This product should be administered orally by hand. For dogs, the daily dose is one tablet per 16 kg bodyweight given orally, providing 30 mg of combined active ingredients per kg bodyweight. Treatment should be continued for up to five days or until two days after symptoms have subsided.

Contra-indications, warnings, etc

FOR ANIMAL TREATMENT ONLY

This dosage form is not suitable for use in cats. Duphatrim 20 Tablets should be administered for this species.

A low incidence of Polyarthropathy and Keratoconjunctivitis Sicca (Dry Eye) has been reported in dogs following oral administration of potentiated sulphonamides. If either of these conditions occur, it is recommended that medication is stopped and that future treatment with this or similar products is avoided.

Not recommended for dogs with known hypersensitivity or hepatic dysfunction.

User warnings:

Wash hands after use. If accidental ingestion occurs, seek medical advice immediately.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Protect from light. Keep out of reach and sight of children.

Legal category

POM-V

Packaging Quantities

Plastic containers of 500 tablets.

Further information

This product may be used to continue treatment begun with Duphatrim IS.

Disposal

Dispose of used packaging in household refuse. Unused tablets should be returned to the veterinary surgeon.

Marketing authorisation number

Vm 01596/4189.