Introduction

Company name: Fort Dodge Animal Health

Address: Flanders Road

Hedge End

Southampton SO30 4QH

Telephone: 01489 781711

Fax: 01489 788306

Presentation

A creamy white paste with broad spectrum antibacterial activity. Presented in disposable dial-a-dose plastic syringes for oral administration to horses. Each syringe contains 45 g of product containing:

Trimethoprim	2.6 g
Sulphadiazine	13.0 g

Uses

For the treatment of bacterial infections in horses. Duphatrim Equine Formula is a broad spectrum antibacterial active against a wide range of Gram-positive and Gram-negative organisms. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria, resulting in a level of activity much greater than that obtained from either drug alone. In vitro Duphatrim is effective against Escherichia coli, Corynebacterium equi, Streptococcus spp and Staphylococcus spp.

When susceptible organisms are present Duphatrim Equine Formula may be effective in treating the following conditions:

Alimentary tract infections including diarrhoea, Respiratory tract infections including pneumonia, pleurisy and strangles; wounds, septicaemia and general infections.

Dosage and administration

Dosage

The daily dose is 30 mg combined active ingredients per kg bodyweight. Each syringe provides one daily dose for a 500 kg horse. Each division on the dial-a-dose plunger provided sufficient product to treat 50 kg of bodyweight.

Treatment should be continued for up to five days or until two days after the symptoms have resolved.

Administration

Adjust screw gauge on dial-a-dose plunger to the bodyweight of the horse. Remove cap from nozzle. Place nozzle in corner of mouth. Depress plunger depositing paste on the upper surface of the tongue. Replace cap after use.

Contra-indications, warnings, etc

FOR ANIMAL TREATMENT ONLY

Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other on the same premises.

Use of the product should be based on susceptibility testing and take into account official and local antimicrobial policies.

Not recommended in horses with known hypersensitivity, severe hepatic dysfunction or cardiac arrhythmias.

Withdrawal Periods:

Do not use on horses intended for human consumption.

The horse must have been declared as not intended for human consumption in accordance with the UK's Horse Passport Legislation.

Operator Warning

This product is known to cause allergic reactions in sensitive individuals, do not use this product if you have a known allergy to this or similar products.

Take care to avoid skin contact. In the case of skin contact wash affected area thoroughly. If irritation occurs/persists seek medical attention.

Gloves should be worn whilst handling this product. Wash hands and exposed skin after use.

Take care to avoid accidental eye contact by wearing suitable eye protection. In the case of accidental eye contact flush thoroughly with clean water and seek medical advice.

Pharmaceutical precautions

Do not store above 25°C. Do not freeze. Keep out of the reach and sight of children.

Legal category

POM-V

Packaging Quantities

Plastic disposable dial-a-dose syringes containing 45 g of product, enough for one daily dose for a 500 kg horse.

Further information

Drug absorption may be greater if food is withheld for a few hours prior to dosing.

Disposal

Dispose of any unused product and empty syringes in accordance with guidance from your local waste regulation authority.

Marketing authorisation number

Vm 01596/4188.