Introduction

Company name: Fort Dodge Animal Health

Address: Flanders Road

Hedge End

Southampton SO30 4QH

Telephone: 01489 781711

Fax: 01489 788306

Presentation

Katavac Eclipse is a combination vaccine comprising one vial of a freeze-dried fraction containing live attenuated strains of feline rhinotracheitis virus strain 2112 (104.5 to 106.7 TCID50), feline calicivirus vaccine strain 2113 (105.5 to 107.7 TCID50) and feline panleucopenia virus strain E (105.0 to 106.5 HAID50) and one vial of Feline leukaemia virus (>1.0 RP) inactivated vaccine for veterinary use.

Uses

For the active immunisation of cats and kittens to reduce mortality and clinical signs caused by feline rhinotracheitis virus; to reduce clinical signs due to feline calicivirus; to prevent mortality and clinical signs and reduce the adverse effects on the immune system caused by feline panleucopenia virus infection. For the prevention of persistent viraemia associated with feline leukaemia virus infection. The onset of immunity is from two weeks after the second vaccination. The duration of immunity is at least one year for all four antigens.

Dosage and administration

The vaccination of female cats prior to mating is recommended to provide maternally derived antibody for the kittens.

The vaccine is to be administered subcutaneously to cats of 9 weeks of age or older.

Aseptically reconstitute the contents of the Katavac CHP freeze-dried vial using Fevaxyn FeLV as a diluent.

Vaccination Schedule

Primary vaccination:

A single dose of Katavac Eclipse should be administered from 9 weeks of age followed by a second injection after an interval of 3-4 weeks.

Booster vaccination: Booster vaccinations are recommended every 12 months.

Contra-indications, warnings, etc

FOR ANIMAL TREATMENT ONLY

Do not vaccinate sick cats.

Do not vaccinate cats during pregnancy.

Animals that have received immunosuppressive drugs should not be vaccinated until an interval of at least four weeks has elapsed.

No information is available on the effects of concurrent use of this vaccine with any other product. It is therefore recommended that no other vaccine should be administered within 14 days before or after vaccination with this product.

Do not mix with any other vaccine or immunological product.

In the event of allergic reaction, immediate treatment should be given using epinephrine (adrenaline) intramuscularly and/or a short acting glucocorticoid (e.g. dexamethasone sodium phosphate) intravenously.

Very occasional lethargy, fever, anorexia, vomiting, coughing, sneezing, localised swelling, pain, pruritus or hair loss may occur post vaccination. Hypersensitivity reactions such as urticaria or facial oedema, sometimes accompanied by respiratory signs have been reported.

In case of accidental self-injection/ingestion/spillage on to skin, seek medical advice immediately and show the package insert or label to the physician.

Pharmaceutical precautions

Store and transport refrigerated (2°C - 8°C). Protect from light. Do not freeze.

Keep out of the reach and sight of children.

Use immediately after reconstitution of the freeze-dried vaccine.

Legal category

POM-V

Packaging Quantities

Packs with 10 or 25× 1 ml doses.

Each dose is a combination of one vial of freeze-dried vaccine (Katavac CHP) and one vial of liquid vaccine (Fevaxyn FeLV).

Not all pack sizes may be marketed.

Further information

The effect of higher levels of maternally derived antibodies on the response to vaccination is not known. However, on the basis of field use, it is expected that in the majority of cats, the levels of maternally derived antibodies that will be present at 9 weeks of age will not interfere with the response to vaccination. Vaccination has no known beneficial effect in cats already infected with FeLV. Therefore, diagnostic testing of cats for the presence of feline leukaemia (FeLV) core protein p27 in serum prior to vaccination may be advisable.

The live vaccine strains may spread to unvaccinated animals, but do not cause diseases.

Disposal: Any unused vaccine or waste material should be disposed of in accordance with local requirements.

Marketing authorisation number

Katavac Eclipse Vm 01596/4179