Introduction

FDAH

Company name: Fort Dodge Animal Health

Address: Flanders Road

Hedge End

Southampton SO30 4QH

Telephone: 01489 781711

Fax: 01489 788306

Presentation

A translucent, yellowish, slightly viscous solution containing 1 gram moxidectin per litre.

Uses

Moxidectin is a second generation macrocyclic lactone of the milbemycin family.

For the treatment and control of gastrointestinal roundworms (including inhibited larvae of Ostertagia circumcincta, Haemonchus contortus and Trichostrongylus axei) and lungworm of sheep.

Cydectin 0.1% Oral Drench for Sheep, at the recommended dosage level of 200 mcg moxidectin per kg bodyweight, provides effective control against the following parasites of sheep:

Mature (adult) and immature (L4) gastro-intestinal nematodes

Haemonchus contortus (including inhibited larvae)

Ostertagia circumcincta (including inhibited larvae)

Ostertagia trifurcata

Trichostrongylus axei (including inhibited larvae)

Trichostrongylus colubriformis

Trichostrongylus vitrinus

Nematodirus battus

Nematodirus spathiger

Nematodirus filicollis (adults only)

Strongyloides papillosus (larval stages only)

Cooperia curticei (adults only)

Cooperia oncophora

Oesophagostomum columbianum

Oesophagostomum venulosum (adults only)

Chabertia ovina

Trichuris ovis (adults only)

Adult respiratory tract nematode

Dictyocaulus filaria

Cydectin 0.1% Oral Drench for Sheep has a persistent effect in preventing reinfection by Ostertagia circumcincta and Haemonchus contortus for 5 weeks and Oesophagostomum columbianum for 4 weeks.

Clinical trials have shown that Cydectin 0.1% Oral Drench for Sheep is effective against certain benzimidazole resistant strains of Haemonchus contortus, Ostertagia circumcincta, Trichostrongylus colubriformis and Cooperia curticei.

Cydectin is a member of the avermectin/milbemycin 3-AV class of anthelmintics. Ask your local veterinary practitioner or animal health advisor for recommended parasite management practices for your area to reduce the risk of development of resistance.

Dosage and administration

Dosage

1 ml per 5 kg liveweight to give 0.2 mg moxidectin/kg liveweight.

Administration

Administer as an oral drench using the Cydectin drench gun or any standard drenching equipment. Check dose rates and equipment before drenching commences. Do not exceed stated dose.

Contra-indications, warnings, etc

For animal treatment only.

Do not smoke or eat when using the product.

Wear impermeable rubber gloves during use.

Wash hands after use.

Keep out of the reach of children.

Avoid direct contact with skin and eyes.

Not to be mixed with other Veterinary Medicinal Products before administration.

Environmental safety

Dangerous to fish and aquatic life. Do not contaminate ponds, waterways or ditches with product or used containers. Dispose of any unused product or containers in accordance with guidance from your local waste regulation authority.

Withdrawal Period

Meat and offal:14 days

Milk: 5 days

Pharmaceutical precautions

Protect from light. Do not store above 25°C.

When the container is broached (opened) for the first time, using the in-use shelf-life which is specified on this package insert, the date on which any product remaining in the container should be discarded should be worked out. This discard date should be written in the space provided on the label and carton.

Use within 6 months following the first withdrawal.

Shelf-life is 24 months from date of manufacture.

Legal category

POM-VPS (previously PML)

Packaging Quantities

1, 2.5 and 5 litre containers.

Further information

Cydectin 0.1% Oral Drench for Sheep has a wide margin of safety and symptons of overdose do not generally occur at less than 5 times the recommended dose.

Dosing Guidelines

Cydectin 0.1% Oral Drench for Sheep gives optimal pasture protection against stomach worms Ostertagia sp and Haemonchus sp, with an 8 week dosing interval–i.e. 5 week persistent activity, plus a 3 week interval from any re-infection to the presence of eggs in the dung.

Ewes

Treat at or around lambing to minimise the ``spring rise'', and pre-tupping, when rams should be treated also.

After treatment, Cydectin 0.1% Oral Drench for Sheep continues to kill stomach worms picked up by the ewe for 5 weeks, thus substantially reducing pasture contamination. This ``vacuum-cleaning'' effect greatly reduces the worm challenge to lambs grazing the same pasture.

Lambs

The first dose should be given at around 4-6 weeks of age, with a second dose, if required 8 weeks later. Additional treatment may be required where there is a Nematodirus challenge.

Nematodirus

Treat lambs when a challenge is expected. Cydectin 0.1% Oral Drench for Sheep effectively controls Nematodirus at the time of dosing, but as with other available wormers does not offer a persistent effect against Nematodirus.