Introduction

Company name: Genitrix Ltd

Address: Genitrix House

Daux Road

Billingshurst

West Sussex

RH14 9SJ

Telephone: 01403 786345

Fax: 01403 786346

Email: mail@genitrix.co.uk

Website: www.genitrix.co.uk

Qualitative and quantitative composition

Fenbendazole 20mg/ml. Aniseed flavour.

Pharmaceutical form

Palatable aqueous suspension for oral administration.

Pharmacological properties

Lapizole is an oral anti-parasiticide for administration to rabbits for the prevention and treatment of infections caused by Encephalitozoon cuniculi.

Clinical particulars

Target species

Rabbits.

Indications for use

Prevents and treats common internal parasites of rabbits susceptible to fenbendazole including E. cuniculi.

Contra-indications

Lapizole is only for use in rabbits. Do not use in animals other than those indicated.

Special precautions for use

If you are uncertain about the condition of your pet, consult a veterinary surgeon. If symptoms persist, consult a veterinary surgeon.

Interactions

None known.

Amounts to be administered and administration route

Weigh animal carefully before administration to accurately assess the appropriate dose.

Replace bottle cap with pump dispenser. Shake well. Prime the dispenser by pumping the product into a tissue until a full dose is dispensed. Dispose of tissue in domestic refuse. For easy administration hold rabbit firmly but gently and place tip of dosing pump in the side of the rabbit's mouth. Dose by actuating pump at 0.5 ml (1 pump actuation) per 0.5 kg bodyweight. This is equivalent to 20 mg fenbendazole per kg bodyweight. Treatment should be continued at this rate once daily for 28 days. Do not overdose. Shake the bottle well before each daily administration.

Special warnings for each target species

Do not overdose.

Withdrawal periods

Not applicable. For pet animals only. Do not use on animals intended for human consumption.

Special precautions to be taken by the person administering the product

Avoid contact with the skin. Wash hands with soap and water following treatment.

Pharmaceutical particulars

Major incompatibilities

None known.

Special precautions for storage

Do not store above 25oC. Do not freeze. Keep out of direct sunlight.

Keep out of reach of children.

Nature and contents of container

Polypropylene container containing 100ml of suspension and a pump oral dispenser.

Special precautions for the disposal of unused medicinal product or waste materials, if any

After use dispose of empty container with domestic refuse.

Marketing authorisation number

WL19886.

Any other information

E. cuniculi is a protozoal parasite of rabbits which affects the nervous and urinary systems and can cause a number of clinical signs, these include but are not limited to, head tilt, hind limb paralysis or weakness, eye problems and death. It is a common parasite which is frequently sub-clinical but over 50% of animals are seropositive. E. cuniculi is zoonotic and presents a particular risk to individuals who may be immunocompromised. Published data on the efficacy of fenbendazole in the treatment and prevention of E. cuniculi in rabbits indicate that a minimum treatment period of 28 consecutive days at 20 mg/kg bodyweight is required for adequate control.