For oral use only.

Vidalta tablets should be administered at the same time every day, in particular in relation to timing of feeding. Vidalta may be given with food or on an empty stomach, as long as this is not varied from day to day.

Do not break or crush Vidalta tablets.

The aim of treatment is to maintain total thyroxine concentrations (TT4) in the lower end of the reference range. Accordingly, the following dose recommendations for dosing during adjustment and maintenance phases are suggested. However dosing adjustment should be primarily based upon the clinical assessment of the individual cat. Monitoring of TT4, full haematology and liver and kidney parameters is advised at each recommended follow up visit.

The starting dose is a single daily oral administration of one tablet of 15 mg carbimazole per cat. Consideration could be given to a starting dose of Vidalta 10 mg daily where the TT4 concentration is only mildly increased, e.g. between 50 nmol/L and 100 nmol/L.

With the recommended starting dose of one Vidalta 15 mg tablet once daily, total thyroxine concentration (TT4) may decrease to within the euthyroid range (TT4<50 nmol/L) shortly after treatment initiation. A dose adjustment may be required as early as 10 days of treatment.

Dose adjustment should also be performed 3, 5 and 8 weeks after initiation of treatment, depending on both clinical and hormonal responses to treatment.

Follow-up visits every 3 to 6 months are recommended. The dose should be adjusted individually based on clinical signs and total thyroxine concentration (TT4). It is advisable to check TT4 10-14 days after dose adjustment.

The therapeutic dose of Vidalta ranges between 10 mg (one 10 mg tablet) and 25 mg (one 10 mg tablet and one 15 mg tablet) once daily.

Some cats require doses of less than 10 mg carbimazole daily. In these cases, alternative treatment should be used.

Dose increases should not be made in increments of greater than 5 mg. Doses above 20 mg have only been trialled in a small number of cats and should be used with caution.