Dose and route of administration: 5 mg of cimetidine per kg of bodyweight administered three times daily by the oral route. Tablets may be split to facilitate dosing.The concomitant use of appropriate dietary measures is strongly recommended. In clinical trials the efficacy of cimetidine has only been studied concomitantly with a hypoallergenic diet.

Recommended treatment scheme: reduction of vomiting is achieved in about 2 weeks. Animals should however be treated for at least 2 weeks after the remission of clinical signs, so a minimum treatment duration of 28 days is recommended. If considered successful, medication can be stopped. A two-week medication-free period should be allowed to see if vomiting occurs again.

If the dog starts vomiting again after a medication-free period, treatment can be re-initiated, without risk for intolerance. Depending on the response, treatment can be adapted to the individual animal until the response is considered to be adequate and then continued at this level. Dietary measures should always be maintained.