Introduction

Company name: Intervet / Schering-Plough Animal Health

Address: Walton Manor

Walton

Milton Keynes

MK7 7AJ

Telephone: 01908 685685 (Customer Support Centre)

Telephone: 0370 060 3380 (Switchboard)

Fax: 01908 685555

Email: support.uk@intervet.com

Website: www.intervet.co.uk

Presentation

A white oral suspension of fenbendazole as a ready to administer oral anthelmintic for domestic dogs, cats, puppies and kittens. 1 ml contains 100 mg active ingredient fenbendazole.

Uses

A broad spectrum anthelmintic for the treatment of domestic dogs and cats infected with immature and mature stages of nematodes of the gastro-intestinal and respiratory tracts.

Adult dogs and cats

For the treatment of adult dogs and cats infected with gastro-intestinal nematodes and cestodes:

Ascarid spp. (Toxocara canis, Toxocara cati and Toxascaris leonina)

Ancylostoma spp.

Trichuris spp.

Uncinaria spp.

Taenia spp.

Puppies and kittens

For the treatment of puppies and kittens infected with gastro-intestinal nematodes and puppies infected with protozoa (Giardia spp.).

Pregnant dogs

For the treatment of pregnant dogs to reduce prenatal infections with Toxocara canis and the transfer of T. canis and Ancylostoma caninum to the pups via the milk.

Other

Also for the treatment of dogs infected with lungworm Oslerus (Filaroides) osleri or protozoa Giardia spp., and cats infected with lungworm Aelurostrongylus abstrusus.

Also has an ovicidal effect on nematode eggs.

Dosage and administration

Routine treatment of adult cats and dogs

1 ml per 1 kg bodyweight as a single oral dose (= 100 mg fenbendazole/kg bodyweight).

Practical dosage recommendations:

2 to 4 kg	4 ml
4 to 8 kg	8 ml
8 to 16 kg	16 ml
16 to 24 kg	24 ml
24 to 32 kg	32 ml
32 to 64 kg	64 ml

For dogs weighing over 64 kg, an extra 1 ml is required for each additional 1 kg bodyweight.

The dose should be mixed with feed, or administered orally directly after feeding.

Treatment should be repeated when natural reinfestation with parasitic worms occurs. Routine treatment of adult animals with minimal exposure to infection is advisable 2 to 4 times per year. More frequent treatment at 6 to 8 weekly intervals is advisable for dogs in kennels.

Puppies and kittens under six months of age

0.5 ml per kg bodyweight daily for 3 consecutive days given by mouth after feeding to unweaned animals or mixed with food for weaned animals (= 50 mg fenbendazole/kg bodyweight daily for 3 days).

Practical dosage recommendations:

Up to 1 kg	0.5 ml daily for 3 days
1 to 2 kg	1 ml daily for 3 days
2 to 4 kg	2 ml daily for 3 days
4 to 6 kg	3 ml daily for 3 days
6 to 8 kg	4 ml daily for 3 days
8 to 10 kg	5 ml daily for 3 days

For puppies weighing over 10 kg, an extra 0.5 ml is required daily for each additional kg bodyweight.

Puppies should be treated at 2 weeks of age, 5 weeks of age and again before leaving the breeders' premises.

Treatment may also be required at 8 and 12 weeks of age. Thereafter, frequency of treatment can be reduced unless the pups remain in kennels where reinfestation occurs more readily.

Pregnant dogs

1 ml per 4 kg bodyweight daily from day 40 of pregnancy continuously to 2 days post-whelping (approximately 25 days) (= 25 mg fenbendazole/kg bodyweight daily).

Practical dosage recommendations:

4 kg	1 ml daily for approx. 25 days
8 kg	2 ml daily for approx. 25 days
12 kg	3 ml daily for approx. 25 days
20 kg	5 ml daily for approx. 25 days
40 kg	10 ml daily for approx. 25 days

For dogs weighing over 40 kg, an extra 1 ml is required daily for each additional 4 kg bodyweight.

As treatment of pregnant dogs is 98% effective, puppies from these dogs should themselves be treated with a three day course at 2 and 5 weeks of age.

Pregnant cats

Pregnant cats can be safely treated with this product but only require a single treatment at the routine adult dose rate. Administer 1 ml per 1 kg bodyweight as a single dose (=100 mg fenbendazole/kg bodyweight).

Increased dosing for specific infections

For the treatment of clinical worm infestations in adult dogs and cats or Giardia spp. infections in dogs administer 1 ml per 2 kg bodyweight daily for 3 consecutive days (= 50 mg fenbendazole/kg bodyweight daily for 3 days).

For the control of lungworm Oslerus (Filaroides) osleri in dogs administer 1 ml per 2 kg bodyweight daily for 7 consecutive days (= 50 mg fenbendazole/kg bodyweight daily for 7 days).

A repeat course of treatment may be required in some cases.

For the control of lungworm Aelurostrongylus abstrusus in cats administer 1 ml per 2 kg bodyweight daily for 3 consecutive days (= 50 mg fenbendazole/kg bodyweight daily for 3 days).

Benzimidazoles have a wide safety margin and even overdose is unlikely to cause reactions.

Contra-indications, warnings, etc

Direct contact with the skin should be kept to a minimum. Wash hands after use.

Assess bodyweight as accurately as possible before calculating the dosage.

For animal treatment only. Keep out of reach and sight of children.

Pharmaceutical precautions

Do not freeze. Shake container well before use.

Wear impermeable rubber gloves.

Dispose of empty packaging and any remaining product in the household refuse.

Legal category

NFA-VPS

Packaging Quantities

100 ml multidose bottle.

Further information

Nil.

Marketing authorisation number

Vm 01708/4436.

UK authorised veterinary medicinal product.