Do not use in lactating dairy cows or ewes producing milk for human consumption. Do not use in non-lactating dairy cows, including pregnant dairy heifers within 60 days of calving. Do not use in sheep which are intended to produce milk for human consumption within 60 days of lambing. Do not use in cases of known hypersensitivity to ivermectin. Do not administer by the intravenous or intramuscular route.

Treatment of psoroptic mange (sheep scab) with one injection is not recommended because although clinical improvement may be seen, elimination of all mites may not occur. Sheep scab (Psoroptes ovis) is an extremely contagious external parasite of sheep. Following treatment of infected sheep great care must be taken to avoid re-infestation as mites may be viable for up to 15 days off the sheep. It is important to ensure all sheep which have been in contact with infected sheep are treated. Contact between treated, infected and non-treated non-infected flocks must be avoided until at least 7 days after the last treatment.

Do not combine treatment with vaccination against lungworms. If vaccinated animals are to be treated, treatment should not be carried out within a period of 28 days before or after vaccination.

The shedding of nematode eggs can continue for some time after treatment.

In cattle, to avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus or in the spine, it is recommended to administer the product at the end of warble fly activity and before the larvae reach their resting sites.

The product can be administered during pregnancy in cows, ewes and sows. The fertility of males is not affected by administration of the product.

Avermectins may not be well tolerated in all non-target species. Cases of intolerance with fatal results are reported in dogs – especially Collies, Old English Sheepdogs and related breeds and crosses, and also in turtles/tortoises.

Do not smoke, eat or drink while handling the product. Wash hands after use. Take care to avoid self injection: the product may cause local irritation and/or pain at the site of injection.

Meat and offal: 42 days in sheep and cattle. 28 days in pigs. Do not use in lactating dairy cows and sheep producing milk for human consumption. Do not use in non-lactating dairy cows, including pregnant dairy heifers or non-lactating dairy sheep within 60 days of calving/lambing.

Extremely dangerous to fish and aquatic life. Do not contaminate surface waters or ditches with product or used container. Any unused product or waste material should be disposed of in accordance with national requirements.