Introduction

Company name: Janssen Animal Health

A division of Janssen-Cilag Ltd

50-100 Holmers Farm Way

High Wycombe

Buckinghamshire

HP12 4EG

Telephone: 01494 567555

Fax: 01494 567556

Email: ahealth@jacgb.jnj.com

Presentation

Exodus is a ready-to-administer oral wormer for horses and other equines. Each 28.5 g syringe contains 11.4 g pyrantel embonate as active ingredient.

Uses

For treatment and control of adult infections of large and small redworms, ascarids and pinworms found in the gastro-intestinal tract of horses and other equines. Exodus also treats and controls tapeworm infections.

Dosage and administration

One syringe per 600 kg bodyweight as a single oral dose (which is equivalent to one syringe mark per 100 kg bodyweight).

Increased dosing for treatment of Tapeworm infections

Double the routine dose rate and administer on a single occasion, i.e. two syringes per 600 kg bodyweight as a single oral dose (which is equivalent to two syringe marks per 100 kg bodyweight). Assess bodyweight as accurately as possible before calculating the dosage. The use of a ‘weigh band’ is recommended. Administer the paste by squeezing from the syringe onto the back of the horse’s tongue. Raising the horses head sometimes assists in the swallowing process.

Weight	Type	Routine Treatment
Up to 100 kg	Miniature Ponies	Syringe mark 100 kg
101-300 kg	Shetland and other small ponies, foals	Syringe mark 300 kg (½ syringe)
301-400 kg	Dartmoor, New Forest, Welsh	Syringe mark 400 kg
401-500 kg	Light hunters, Arabs, etc	Syringe mark 500 kg
501-600 kg	Thoroughbreds	Syringe mark 600 kg (1 syringe)
>601 kg	Heavy hunters, draught horses	1 full syringe plus additional 100 kg syringe marks for each extra 100 kg bodyweight

Recommended dosing programmes

During the grazing season, all horses over 8 months of age should be wormed with Exodus every 4-6 weeks. For the remainder of the year, horses should be wormed with Exodus every 6-8 weeks.

New horses and horses which have spent the winter inside, should be wormed with Exodus and then kept in for 3-4 days before turnout.

Contra-indications, warnings, etc

Do not administer to horses intended for human consumption. Do not use in severely debilitated animals. Combined administration of pyrantel and levamisole or piperazine is not recommended.

Operator warnings

Direct contact with the skin should be avoided; wash hands and any other parts of the body which come into contact with the product after use. Avoid handling the product if you know you are hypersensitive to pyrantel. The same syringe should only be used to dose two animals if they are both healthy and are either grazing together, or are on the same premises and in direct contact with each other.

Exodus is suitable for horses and ponies over one month of age, including suckling foals, pregnant mares and stallions. Impaction of the small intestines may occur in foals heavily infected with Ascarids. Colic symptoms may be seen as soon as 30 minutes after treatment.

Use during pregnancy and lactation

Exodus is suitable to give to pregnant and lactating mares provided the recommendations are followed.

Pharmaceutical precautions

Keep out of reach of children. Do not store above 25 °C. Protect from direct sunlight. On occasions where only part of the paste is used, replace the cap and store as indicated.

Disposal

Dispose of used syringes in the farm refuse. Used syringes should not be recycled.

Legal category

POM-VPS

Packaging Quantities

Each 28.5 g syringe contains 11.4 g pyrantel embonate as active ingredient.

Further information

Nil

Marketing authorisation number

Vm 12597/4041.