Introduction

vet06701

Company name: Janssen Animal Health

A division of Janssen-Cilag Ltd

50-100 Holmers Farm Way

High Wycombe

Buckinghamshire

HP12 4EG

Telephone: 01494 567555

Fax: 01494 567556

Email: ahealth@jacgb.jnj.com

Presentation

A ready-to-administer 18.7 mg/g ivermectin oral paste formulation with apple flavour.

Uses

For broad spectrum use of parasite control in horses, ponies, mares and foals. Maximec kills the adult and larval stages of most of the important internal parasites including small redworms, the arterial stages of the large redworms, lungworms and bots with a single dose. Maximec kills small redworms that are resistant to benzimidazole-based wormers. Maximec controls the following horse parasites with one easy treatment:

Large Redworms

adult and arterial larval stages of Strongylus vulgaris

adults and tissue larval stages of S. edentatus

adults of S. equinus

Craterstomum acuticaudatum

Triodontophorus spp.

Small Redworms

adult and immature stages including strains that are resistant to benzimidazole-based wormers

Coronocyclus spp.

Cyathostomum spp.

Cylicocyclus spp.

Cylicostephanus spp.

Cylicodontophorus bicornatus

Gyalocephalus capitatus

Paraposteriostomum spp.

Petrovinema poculatum

Poteriostomum imparidentatum

Pinworms

adult and immature Oxyuris equi

Lungworms

adult and immature Dictyocaulus arnfieldi

Ascarids

adult and immature Parascaris equorum

Stomach worms

Trichostrongylus axei

Habronema muscae

Intestinal threadworms

Strongyloides westeri

Cutaneous worms

microfilariae of Onchocerca spp.

Bots

mouth and stomach stages of Gasterophilus spp.

Dosage and administration

Each syringe contains sufficient paste to treat one 600 kg horse at the recommended dose rate of 200 micrograms of ivermectin per kg of bodyweight. Each weight marking on the syringe plunger delivers sufficient paste to treat 100 kg of bodyweight.

Using the syringe

Release the knurled ring by making a quarter turn and slide the ring up the plunger shaft so that the side of the ring nearest the barrel is at the desired weight marking. Turn the knurled ring a quarter turn to lock in place. Make sure the horse's mouth contains no feed. Remove the plastic cap from the tip of the syringe barrel and insert the syringe at the interdental space (the gap between the front and back teeth). Depress the plunger and deposit the paste over the back of the tongue. Immediately raise the horse's head for a few seconds after dosing.

For best results

All horses should be included in a regular parasite control programme, with particular attention being paid to mares, foals and yearlings. Foals should be treated initially at 6 to 8 weeks of age, and routine treatment repeated as appropriate. The product is highly effective against gastro-intestinal, cutaneous and pulmonary nematodes and bots of horses. Regular treatment will reduce the chances of verminous arteritis and colic caused by Strongylus vulgaris. With its broad spectrum, the product is well suited to be the major medication in parasite control programmes, and is well suited to be a major component in a rotational programme.

Contra-indications, warnings, etc

Maximec has been formulated specifically for use in horses only. Some horses have experienced reactions involving cutaneous swelling and itching shortly after treatment. In most such cases, the horses have been diagnosed as carrying heavy infections of Onchocerca microfilariae, and it is assumed the reactions were the result of microfilariae dying in large numbers. Although the signs have resolved spontaneously in a few days, symptomatic treatment may be advisable. Consult your Veterinary Surgeon should these signs persist.

Dogs or cats may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.

Do not smoke, drink or eat while handling the product. Wash hands after use.

Withdrawal period

Horses should not be slaughtered for human consumption within 21 days of treatment. Not permitted for use in lactating mares producing milk for human consumption.

Disposal

Do not contaminate surface waters or ditches with product or used containers. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Pharmaceutical precautions

For animal treatment only. Keep out of the reach and sight of children.

Legal category

POM-VPS

Packaging Quantities

Display carton with 24 syringes each containing 6.42 g.

Further information

Derived from naturally occurring substances. The active ingredient, ivermectin, is produced from a naturally occurring fungus Streptomyces avermitilis. Maximec has a wide safety margin. At the recommended rate, it can be used with complete confidence in foals, mares, ponies and horses. Mares may be treated at any stage of pregnancy and the fertility of stallions that have been treated has not been affected.