Rainfall at any time before or after treatment will not affect the efficacy of the product.

While mite and louse numbers decline rapidly following treatment, due to the feeding habits of the parasites, in some cases several weeks may be required for complete eradication.

No signs of toxicity appeared when 8-week old calves were treated at up to 5 times the therapeutic dose (i.e. 2.5 mg eprinomectin per kg bodyweight), 3 times at 7-day intervals. One calf treated once at 10 times the therapeutic dose (i.e. 5 mg per kg bodyweight) in the tolerance study showed transient mydriasis. There were no other adverse reactions to treatment. No antidote has been identified.