Inactivated vaccine in an oily adjuvant against Newcastle Disease, Infectious Bronchitis, Egg Drop Syndrome (EDS76) and Avian Rhinotracheitis. The vaccine stimulates active immunity of breeder and layer pullets against Egg Drop Syndrome (EDS76) (without priming), Newcastle Disease, Infectious Bronchitis and Avian Rhinotracheitis (Swollen Head Syndrome), subsequent to priming with live vaccines against these diseases.