Oramec Drench (ivermectin)
Company name: Merial Animal Health Ltd
Address: PO Box 327
Sandringham House
Harlow Business Park
Harlow
Essex CM19 5TG
Telephone: Companion Animals 0870 6000123
Production Animals 0800 592699
Fax: 01279 775888
Email: ukenquiry@merial.com
Website: www.merial.com
A pale yellow free-flowing aqueous solution containing 0.08% w/v ivermectin for oral administration. Contains benzyl alcohol as preservative.
For the treatment and control of gastro-intestinal nematodes, lungworms and nasal bots of sheep.
ORAMEC DRENCH at the recommended dose rate of 200 micrograms ivermectin per kg bodyweight provides effective control against the following parasites of sheep.
Gastro-intestinal roundworms (adult and immature): Haemonchus contortus, Ostertagia circumcincta, Trichostrongylus spp., Cooperia spp., Nematodirus spp. including N. battus, Strongyloides papillosus, Oesophagostomum spp. and adult Chabertia ovina.
Inhibited larval stages and benzimidazole-resistant strains of Haemonchus contortus and Ostertagia circumcincta are also controlled.
Lungworms (adult and immature): Dictyocaulus filaria.
Nasal bot (all larval stages): Oestrus ovis.
Dosage
2.5 ml per 10 kg bodyweight (corresponding to the recommended dose rate of 200 micrograms ivermectin per kg bodyweight), administered orally with a dosing gun. The dosing gun should be calibrated sufficiently accurately to ensure precise dosing of young sheep.
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Do not mix with other products.
Administration
Give as an oral drench.
Contra-indications, warnings, etc
For animal treatment only.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to macrocyclic lactones (which includes ivermectin) has been reported in Teladorsagia spp. in sheep within the EU. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Do not smoke, eat or drink while handling the product.
Wash hands after use.
Avoid contact with skin and eyes.
In case of accidental spillage onto the skin or eyes, wash the affected area with clean running water immediately. Seek medical attention if irritation persists.
ORAMEC DRENCH has been formulated specifically for use in sheep. It should not be used in other species, as severe adverse reactions, including fatalities in dogs, may occur.
Withdrawal periods
Animals must not be slaughtered for human consumption during treatment.
Sheep may be slaughtered for human consumption only from 6 days after the last treatment.
Do not use in lactating animals producing milk for human consumption.
If milk is to be used for human consumption animals should not be treated within 60 days prior to the commencement of lactation.
Container disposal
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Do not store above 25°C. Protect from direct sunlight.
Keep out of the reach and sight of children.
Some animals may cough slightly immediately after treatment. This passing response is of no consequence.
ORAMEC DRENCH can be administered to ewes at any stage of pregnancy. ORAMEC DRENCH will not affect the fertility of breeding ewes and rams and can be given to all ages of animals including young lambs.
ORAMEC DRENCH has demonstrated a wide safety margin at the recommended dose level. ORAMEC DRENCH may be used in sheep of all ages. During a study to assess toxicological effects only mild incoordination and depression were observed at 20 x the recommended dose level (4 mg ivermectin per kg bodyweight administered by stomach tube). At 40 x the recommended dose level (8 mg ivermectin per kg bodyweight administered by stomach tube) acute symptoms (ataxia, staggering gait, incoordination and depression) were observed. Within 24 hours nearly all animals appeared normal and within 3 days all animals appeared clinically normal.
No antidote has been identified. However, symptomatic treatment may be beneficial.
Ivermectin is a member of the macrocyclic lactone class of endectocides.