Trodax 34%
Introduction
Company name: Merial Animal Health Ltd
Address: PO Box 327
Sandringham House
Harlow Business Park
Harlow
Essex CM19 5TG
Telephone: Companion Animals 0870 6000123
Production Animals 0800 592699
Fax: 01279 775888
Email: ukenquiry@merial.com
Website: www.merial.com
Presentation
Solution for injection containing nitroxynil (as N-ethylglucamine salt) 34% w/v.
Uses
TRODAX 34% solution is indicated for the treatment of fascioliasis (infestations of mature and immature Fasciola hepatica) in cattle and sheep. It is also effective, at the recommended dose rate, against adult and larval infestations of Haemonchus contortus in cattle and sheep and Haemonchus placei, Oesophagostomum radiatum and Bunostomum phlebotomum in cattle. However, TRODAX 34% should not be regarded or used as a broad spectrum anthelmintic.
Dosage and administration
Administer by subcutaneous injection.
The standard dosage is 10mg nitroxynil per kilogram bodyweight.
Sheep: Administer according to the following doses scale:
Liveweight (kg) | Dose (ml) |
14-20kg | 0.5 |
21-30kg | 0.75 |
31-40kg | 1.0 |
41-55kg | 1.5 |
56-75kg | 2.0 |
Over 75kg | 2.5 |
On farms with fluke-infested pastures, routine dosing should be carried out at intervals of not less than 49 days (7 weeks), having regard for such factors as the past disease history of the farm, the frequency and severity of neighbouring outbreaks and regional forecasts of incidence.
In outbreaks of acute fascioliasis advice on the best treatment should be sought from a veterinary surgeon.
Cattle: 1.5ml of TRODAX 34% per 50kg (1cwt) liveweight.
Both infected and in-contact animals should be treated, treatment being repeated as considered necessary, though not more frequently than once per 60 days. The treatment of cattle helps reduce contamination of pastures on farms where fascioliasis is endemic or certain roundworm occurrence is evident.
Contra-indications, warnings, etc
For animal treatment only.
Do not use in animals with known hypersensitivity to the active ingredient.
Do not use in animals producing milk for human consumption.
Do not exceed stated dose.
Small swellings are occasionally observed at the injection site in cattle. These can be avoided by injecting the dose in two separate sites and massaging well to disperse the solution.
No systemic ill effects are to be expected when animals (including pregnant cows and ewes) are treated at normal dosage.
Ensure the injection does not enter subcutaneous muscle.
Ewes in advanced pregnancy should be handled and dosed carefully.
Estimate the weight of the sheep carefully and use injection equipment calibrated to accurately deliver the calculated dosage.
TRODAX 34% solution stains and care should be taken not to spill it, especially on the fleece of sheep.
In the event of accidental overdose, the symptoms are pyrexia, rapid respiration and increased excitability. Patients should be kept cool, and dextrose saline should be administered intravenously.
Do not retreat at intervals less than 60 days (cattle) or 49 days (sheep).
Wear impermeable gloves to avoid staining the skin. Wash splashes from skin and eyes immediately.
Obtain medical help if irritation persists.
In case of accidental or deliberate ingestion, wash out the mouth with water and obtain medical help.
Care must be taken to avoid accidental self-injection. Seek medical assistance in case of accidental injection.
Withdrawal periods
Cattle may be slaughtered for human consumption only after 60 days from the last treatment. Sheep may be slaughtered for human consumption only after 49 days from the last treatment.
Pharmaceutical precautions
Do not dilute or mix with other compounds.
Once the container has been broached use the contents within 28 days.
Do not store above 25°C, protect from light.
Keep out of the reach and sight of children.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Legal category
POM-VPS
Packaging Quantities
Multi-dose containers of 250 ml and 2x500ml.
Further information
Nitroxynil is active against triclabendazole-resistant Fasciola hepatica.
No signs of incompatibility are to be expected if TRODAX 34% is administered to cattle or sheep concurrently with therapeutic doses of levamisole, or with clostridial vaccine.
TRODAX 34% is safe for use in pregnant animals.
Marketing authorisation number
Vm 08327/4187.