In-feed use.

The uptake of medicated feed depends on the clinical condition of the animal. In order to obtain the correct dosage the concentration of Econor has to be adjusted. Inclusion levels may also need to be increased in older pigs or pigs on restricted feed to achieve target dosage

The dosage is 3-4 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% premix at a level of 750 g/tonne feed to provide 75 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for a minimum of 7 days and up to 4 weeks or until signs of disease disappear. This dose level is effective in the treatment of clinical disease, but higher dosages or longer duration of treatment may be necessary for complete elimination of infection. It is important to institute medication as early as possible in an outbreak of swine dysentery. If there is no response to treatment within 5 days, the diagnosis should be re-established.

The dosage is 3 - 4 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% premix at a level of 750 g/tonne feed to provide 75 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for 2 weeks or until signs of disease disappear. This dose level is effective under normal situations in the treatment of clinical signs of the disease, but higher dosages or longer duration of treatment may be necessary for complete elimination of infection. It is important to institute medication as early as possible in an outbreak of porcine proliferative enteropathy. If there is no response to treatment within 5 days , the diagnosis should be re-established. For severely affected animals which fail to respond to treatment within 3 – 5 days, parenteral treatment should be considered.

The dosage is 1.0 - 1.5 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% premix with the final feed at a level of 250 g/tonne feed to provide 25 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for a minimum of 7 days and up to 4 weeks.

The dosage is 1.0 - 1.5 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% premix with the final feed at a level of 250 g/tonne feed to provide 25 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for 4 weeks.

Long term preventative use of valnemulin should be avoided by improving management practice and thorough cleansing and disinfection. Consideration should be given to the eradication of infection from the farm.

The dosage is 10 - 12 mg/kg bodyweight per day. This is normally achieved, for example, in grower pigs, by incorporating Econor 10% premix at a level of 2 kg/tonne to provide 200 mg active substance per kg feed depending on pigs’feed intake. The medicated feed should be fed as the sole ration daily for up to 3 weeks.

Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication.

mg Econor 10% premix/kg feed = Dosage required (mg/kg) x 10 x bodyweight (kg)/Daily feed intake (kg)

The product has been shown to be stable to the pelleting process at temperatures of 75°C. Aggressive pelleting conditions such as temperatures in excess of 80°C and the use of abrasive substances for pre-mixture should be avoided.

To achieve good mixture and homogeneity of incorporation the use of a pre-mixture is recommended. The required quantity of product is thoroughly mixed with a feed ingredient of similar physical nature (e.g. wheat middlings) in the proportion: 1 part Econor 10% premix to 10 parts feed ingredient.

Consideration should be given to official guidance on the incorporation of medicated premixes in final feeds.