Interaction with other medicinal products and other forms of interaction : None Known

The veterinary medicinal product is an insecticidal and acaricidal solution for spot-on use, containing pyriprole as active ingredient.

Pyriprole is an insecticide and acaricide belonging to the phenylpyrazole class. It acts by interacting with ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. This results in uncontrolled activity of the central nervous system and death of fleas and ticks.

Parasites are killed through contact rather than by systemic exposure. Pyriprole kills fleas within 24 hours and ticks (Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus, Ixodes scapularis, Dermacentor variabilis, Amblyomma americanum) within 48 hours post-exposure.

Adult fleas are killed before they lay eggs for a minimum of 4 weeks after treatment. Since Prac-tic completely eliminates egg production, it breaks the flea life cycle.