NOAH Compendium of Animal Medicines: Alzane 5 mg/ml Solution for Injection for Dogs & Cats

Alzane 5 mg/ml Solution for Injection for Dogs & Cats

Dosage and administration

For single intramuscular injection in dogs and cats. Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes. Atipamezole is generally administered 15-60 minutes after medetomidine or dexmedetomidine injection.

Dogs: The dose of atipamezole hydrochloride (in µg) is five times that of the previous dose of medetomidine hydrochloride or ten times that of the dose of dexmedetomidine hydrochloride. Due to the fivefold concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the tenfold concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, an equal volume of each preparation is required.

Dosage example dogs:

Medetomidine 1.0 mg/ml solution for injection dosage	Alzane 5.0 mg/ml solution for injection dosage
0.04 ml/kg bodyweight (bw), corresponding with 40 μg/kg bw	0.04 ml/kg bodyweight (bw), corresponding with 200 μg/kg bw
Dexmedetomidine 0.5 mg/ml solution for injection dosage	Alzane 5.0 mg/ml solution for injection dosage
0.04 ml/kg bodyweight (bw), corresponding with 20 μg/kg bw	0.04 ml/kg bodyweight (bw), corresponding with 200 μg/kg bw

Cats: The atipamezole hydrochloride dose (in µg) is 2.5 times that of the previous dose of medetomidine hydrochloride or five times that of the dose of dexmedetomidine hydrochloride. Due to the fivefold concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the tenfold concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, half the volume of the product to that of the previously administered medetomidine or dexmedetomidine should be given.

Dosage example cats:

Medetomidine 1.0 mg/ml solution for injection dosage	Alzane 5.0 mg/ml solution for injection dosage
0.08 ml/kg bodyweight (bw), corresponding with 80 μg/kg bw	0.04 ml/kg bodyweight (bw), corresponding with 200 μg/kg bw
Dexmedetomidine 0.5 mg/ml solution for injection dosage	Alzane 5.0 mg/ml solution for injection dosage
0.08 ml/kg bodyweight (bw), corresponding with 40 μg/kg bw	0.04 ml/kg bodyweight (bw), corresponding with 200 μg/kg bw

The recovery time is shortened to approximately 5 minutes. The animals become mobile after approximately 10 minutes after administration of the product.