Dermisol Multicleanse Solution Dosage and administration For topical application only. 1.General cleansing. The solution should be used generously to remove dirt, grit, coagulum, etc. The residual solution will promote sloughing of devitalised tissues. 2.Otitis externa. Use liberally to clean the ear canal. Where hardened wax is present the solution may be left in situ, thereby softening the wax and allowing easy removal next day. The application may be repeated 2–3 times daily as necessary.