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Lutalyse 5 mg/ml Solution for Injection:  Contra-indications, warnings, etc
 
 
Lutalyse 5 mg/ml Solution for Injection
Lutalyse 5 mg/ml Solution for Injection
Contra-indications, warnings, etc
Prostaglandins of the Ftype can be absorbed through the skin and may cause bronchospasm or miscarriage.
Care should be taken when handling the product to avoid self-injection or skin contact.
Women of child-bearing age, asthmatics and persons with bronchial or other respiratory problems should avoid contact with, or wear disposable plastic gloves when administering the product.
Accidental spillage on the skin should be washed off immediately with soap and water. Wash hands after use.
Cattle: Localised post injection bacterial infections that may become generalized have been reported. Aggressive antibiotic therapy should be employed at the first sign of infection. Careful aseptic techniques should be employed to decrease the possibility of post injection bacterial infections.
Withdrawal periods:
Cattle milk: zero hours.
Cattle meat: 1 day.
Pig meat: 1 day.
Horses: not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse passport must have been declared as not intended for human consumption under national horse passport legislation.
Animals should not be treated if they suffer from either acute or sub-acute disorders of the vascular system, gastro-intestinal tract or respiratory system.
Contra-indicated when abortion or parturition is not intended.
Pregnancy status should be determined prior to injection since Lutalyse has been demonstrated to result in abortion or parturition induction when administered at sufficiently high doses to many animal species.
Do not administer by the intravenous route.
Lutalyse is ineffective when administered prior to day five after ovulation.
If pregnant, the unlikely possibility of uterine rupture should be borne in mind, especially if cervical dilation does not occur.
Induction of parturition in pigs earlier than 72 hours prior to predicted farrowing date may result in reduced piglet viability.
Side-effects
Cattle: The most frequently observed side-effect is increased rectal temperature at a 5 × or 10× overdose. However, rectal temperature changes have been transient in all cases observed and have not been detrimental to the animal. Limited salivation has been seen in some instances.
Horses: The most frequently observed side-effects are sweating and decreased rectal temperature. However, these have been transient in all cases observed and have not been detrimental to the animal. Other reactions seen have been increase in heart rate, increase in respiration rate, some abdominal discomfort, locomotor incoordination and lying down. These effects are usually seen within 15 minutes of injection and disappear within one hour. Mares usually continue to eat during the period of expression of side-effects.
Pigs: Transient side-effects consisting of increased body temperature, increased respiratory rate, increased salivation, stimulation of defaecation and urination, flushing of the skin and restlessness (arching of back, pawing, and rubbing and gnawing the crate) occur occasionally following the administration of dinoprost in pregnant sows and gilts. These effects tend to parallel the signs exhibited by sows prior to normal parturition, only they appear to be condensed in time. These effects are usually seen within 15 minutes of injection and disappear within one hour.
           
 
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  Date updated: 12 July 2013