Remove the Stronghold tube from its protective package. Holding the tube upright, firmly depress the cap to puncture the applicator seal, then remove the cap. Part the hair at the base of the animal’s neck in front of the shoulder blades to expose a small area of skin. Apply the tip of the Stronghold tube directly to the skin without massaging. Squeeze the tube firmly to empty the contents in one spot. Avoid contact between Stronghold and fingers. Stronghold should be administered as a single topical application of a unit dose delivering a minimum of 6 mg/kg selamectin. When concurrent infestations or infections in the same animal are to be treated with Stronghold, only one topical application of the recommended 6 mg/kg dose should be administered at any one time.