The use of tetracyclines during the period of tooth development, including late pregnancy, may lead to tooth discolouration.

Interactions may occur with solutions with high calcium, magnesium or sodium content.

The safety margin of oxytetracycline in the target species is very wide and toxic signs are unlikely to be seen. Large overdoses are potentially nephrotoxic.

Acutely ill animals are unlikely to consume an adequate dose unless treated by drinking water or drench methods.

When given via the drinking water remove all other sources of water until the medicated water has been consumed.

Following oral dosage in ruminating animals changes in the ruminal flora may occur but these have generally been found to be of a transitory and reversible nature. Administration of Terramycin at the recommended dosage will usually result in only a small depression of cellulose digestion.

To reconstitute the powder in drinking water, it should be agitated in vigorously in a small volume of water and added to the bulk tank when fully dissolved.

Bacterial resistance may develop after long term use of oxytetracycline. This is particularly likely in Enterobacteria and Salmonella, many of which are already resistant.

Salmonella shedding in treated animals will continue where organisms are resistant.

Wash hands after use.

Cattle: Meat – 10 days.

Milk – zero days.

Milk for human consumption must not be taken during treatment.

Pigs: 7 days.

For animal treatment only.

Keep out of reach of children.