Introduction

Company name: Pfizer Limited

Address: Ramsgate Road

Sandwich

Kent CT13 9NJ

Telephone: 0845 300 8034 (Out of hours: 01304 616161)

Fax: 01737 332521

Email: UKVetLine@pfizer.com

Website: www.only4vets.co.uk

Presentation

A pale yellow to light tan soluble powder for dissolution in water. Each pack contains (to give 100 g combined antibiotic activity):

Lincomycin, 33.3 g (as Lincomycin Hydrochloride) and Spectinomycin, 66.7 g (as spectinomycin sulphate). Also contains sodium benzoate 4.1 g as preservative.

Uses

Pigs: For the treatment of enteritis caused by Lawsonia intracellularis (ileitis).

Poultry: Antibacterial or antimycoplasmal therapy against sensitive organisms.

For the treatment and prevention of Chronic Respiratory Disease (CRD) associated with mycoplasma and coliform infections of growing poultry susceptible to the action of the antibiotic combination.

Dosage and administration

Linco-Spectin 100 Soluble Powder is formulated for administration via drinking water.

Pigs

A fresh solution should be prepared each day. Treatment should be started as soon as first symptoms first occur. The recommended dosage is 10 mg/kg body weight per day and is achieved by administering 63 mg antibiotic activity (21 mg lincomycin + 42 mg spectomycin) per litre. This medicated water must be the sole source of drinking water or the pigs over the duration of the treatment, 7 days.

Mixing Directions

To achieve the required dose rate dissolve the contents of one tub (150 g) of Linco-Spectin 100 Soluble Powder in 1600 litres of drinking water.

Poultry

A fresh solution should be prepared each day. Linco-Spectin 100 Soluble Powder is formulated for administration as the sole daily source of drinking water until consumed, followed by non-medicated water for the rest of the day, if necessary.

Prevention of CRD

1. Administer 150 mg of antibiotic activity (=50 mg lincomycin +100 mg spectinomycin) per kg body weight per day for the first three to five days of life.

2. Administer 50 mg of antibiotic activity per kg of body weight per day for one to two days during the fourth week of age or after vaccination.

Treatment of CRD

Administer 50 mg of antibiotic activity per kg of body weight per day at the first signs of disease and continue to three to seven days.

Dosage Table

per 1000 birds daily (at 150 mg/kg antibiotic activity)

Birds Average Wt (g)	Grams Linco-Spectin 100 Soluble Powder Required for 1000 birds	Litres of Water
40	9	12
100	22.5	30
200	45	60
500	112.5	150
1000	225	300
2000	450	600

For 50 mg/kg daily dose, divide grams of Linco-Spectin and litres of water by 3.

Contra-indications, warnings, etc

Pigs

Loosening of faeces and/or mild swelling of the anus may occur, this is usually transient. On rare occasions mild irritability and reddening of the skin may occur. These conditions are usually self correcting within five to eight days without discontinuing therapy.

Poultry

Do not administer to poultry producing eggs for human consumption.

Do not administer to horses, ruminating animals, guinea pigs and rabbits.

Operator warning

Persons known to be hypersensitive (allergic) to lincomycin, spectinomycin or soybean millfeed should not handle the product.

Care should be taken not to inhale any dust. The wearing of approved dust masks (either a disposable half-mask respirator conforming to European Standard EN 149 or a non disposable respirator to European Standard EN 140 with a filter to EN 143) and safety glassed is recommended during the handling and mixing of this product.

Skin contact should be avoided. Wash hands and any exposed skin with soap and water immediately after use.

Keep out of reach of children. For animal treatment only.

Withdrawal Periods

Pigs

Nil

Poultry

Birds must not be slaughtered for human consumption during treatment. Birds may be slaughtered for human consumption 5 days after last treatment.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Any medicated water which is not consumed within 24 hours should be discarded.

Disposal advice

Dispose of any unused product, empty containers and any medicated water which is not consumed within 24 hours in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Packaging Quantities

Supplied in a 150 g plastic container.

Further information

When an antibiotic treatment programme is prescribed, consideration should be given to ensuring that good management practices are also in place.

Marketing authorisation number

Vm 00057/4236.