Company name: Zoetis UK Limited
Address: 5th Floor
6 St Andrew Street
London EC4A 3AE
Telephone: 0845 300 8034
Fax: 01737 332521
Lyophilisate and solvent for suspension for injection.
Colombovac PMV/Pox is presented in two vials.
Colombovac PMV/Pox comprises one vial of liquid inactivated, adjuvanted avian paramyxovirus serotype 1 (PMV-1) vaccine able to stimulate antibody titres of 27.0 to 29.5 and one vial of freeze dried pigeon pox (DD strain) vaccine containing 103.5 to 104.3 TCID50/dose of attenuated virus.
Reconstitute one Colombovac Pox vial containing the freeze dried pox vaccine with the contents of one vial of the liquid Colombovac PMV paramyxovirus vaccine, immediately for use.
For the primary and booster vaccination of healthy, susceptible, immune competent pigeons against paramyxovirus infection caused by the PMV-1 serotype and as an aid in the protection against pigeon pox virus infection.
Shake the liquid Colombovac PMV vial before withdrawing all of the contents. Inject all of this liquid vaccine into one vial containing the freeze dried pellet of Colombovac Pox vaccine. Shake again before use.
Administer 0.2ml of reconstituted vaccine by subcutaneous injection.
Inject 0.2ml of the reconstituted combined vaccine dorsally in the neck region, in the direction of the back.
1.Racing pigeons: All birds in the loft should be given a vaccination annually from the early new year not less than 21 days before the beginning of the racing season.
Birds may be vaccinated with Colombovac PMV/Pox from 6 weeks of age when a single injection will provide immunity for 1 year for paramyxovirus and throughout the greatest season for risk for pox, the spring and summer months, when vaccinated in the first quarter of the year. Following vaccination avoid contact with birds from other lofts for at least 21 days to allow immunity to develop.
All late-hatched young pigeons should be given one vaccination from 6 weeks of age and not mixed with birds from other lofts for at least 21 days.
All adult birds in the loft should be given a single booster vaccination annually from the early new year. Where the annual booster vaccination may interfere with the training or racing programme, it may be brought forward prior to the commencement of each racing season.
2.Show pigeons: All birds on the premises should be given one vaccination annually not less than 21 days before the beginning of the show season.
Birds may be vaccinated with Colombovac PMV/Pox from 6 weeks of age when a single injection will provide immunity for 1 year for paramyxovirus and throughout the greatest season for risk for pox, the spring and summer months when vaccinated in the first quarter of the year. Following vaccination avoid contact with birds from other lofts for at least 21 days to allow immunity to develop.
All adult birds on the premises should be given a single booster vaccination annually from the early new year.
FOR ANIMAL TREATMENT ONLY
KEEP OUT OF REACH AND SIGHT OF CHILDREN
Use entire contents of both vials when first opened.
Use within 2 hours of reconstitution.
Dispose of used containers by incineration.
Do not use within the 14 days before or 14 days after the administration of other vaccines.
Only healthy birds should be vaccinated.
As vaccination can be disruptive during the breeding season, it is advised that birds are not vaccinated from pairing up until production of the first egg.
Administer the vaccine only by the subcutaneous route. Aseptic precautions should be observed at all times.
Occasionally a transient swelling at the site of injection may occur.
In cases of anaphylactoid reaction, treat immediately with glucocorticoid intravenously or adrenaline intramuscularly.
Store and transport refrigerated (2°C-8°C). Do not freeze.
Protect from light.
Wash hands after use. Dispose of unused containers by incineration.
Do not use after the stated expiration date.
A pack comprising:
One vial containing 50 doses of freeze dried Colombovac Pox vaccine.
One vial containing 50 doses of liquid Colombovac PMV vaccine.
An owner should prohibit visit to the loft by anyone in contact with unvaccinated pigeons and new birds (either purchased or lent for mating) should not be brought-in unless vaccinated at least 21 days previously
The incubation period for Pigeon Paramyxovirus may be a few days to several weeks. However, after infection with the wild virus, pigeons excrete the virus from the eye and in the droppings within 3-4 days. This means that infected birds can be a danger to others some days before their own symptoms appear. Excretion of wild virus from the infected bird continues for up to 6 weeks.
In addition to direct bird to bird contact at competitions and shows, the disease can be spread by indirect means such as hands, overalls, cap, boots and contaminated objects such as baskets and trucks.
The incubation period of Pigeon Pox is usually 5 to 15 days and the disease may manifest as crusty skin lesions around the eye, beak and on the feather follicles, or mucosal, diphtheroid lesions of the larynx or gullet. Virus may be excreted in saliva, nasal and eye secretions but rarely in the droppings, and is also present in crusty scab material from any skin lesions. Virus can be spread directly from bird to bird, or via feeding or drinking utensils or by other direct means. A pigeon from an infected loft can carry the pox virus and may infect other birds without itself showing signs of disease.
In any animal population there will be a small number of individuals which fails to respond fully to vaccination. Successful vaccination depends upon correct storage and administration of vaccine and the animal’s ability to respond. Immune competence can be influenced by genetic factors, intercurrent infection, age, nutritional status, concurrent drug therapy, stress, etc.
Maternally derived antibody (MDA) can interfere with the development of active immunity. Where it is likely that recent field infection or vaccination of the parent flock has stimulated a high antibody titre and consequently a high level of MDA, the timing of the vaccination programme should be planned accordingly. The advice of your veterinary surgeon may be sought in such cases.