Hypermune-RE may be administered to foals from 24 hours to 6 days of age where it has been shown after testing that they have low levels of serum IgG (less than 4 g/l). The dose required is one litre for a 50 kg foal (and pro rata, i.e. 20 ml per kg).

A blood sample should be collected from the foal approximately 24 hours later and re-tested for the level of serum IgG. If this is still low, a further dose may be administered. This should be given within 24 – 48 hours of the first administration and be given in the same manner as the first (intravenously, via a blood giving set, over 15 - 20 minutes).

For foals with Normal Passive Transfer The dose required is one litre for a 50 kg foal (and pro rata, i.e. 20 ml per kg). To sustain raised levels of circulating Rhodococcus equi antibodies a second dose may be given at approximately 21 days later. This should be given in the same manner as the first (intravenously, via a blood giving set, over 15 - 20 minutes).

The required dose is administered via a catheter placed in the jugular vein using a blood giving set equipped with a mesh filter. The product should be administered slowly, particularly at the start, and administration should take 15 – 20 minutes. Throughout the administration, the foal should be monitored for signs of adverse reactions.

The foal may be mildly sedated if necessary the skin anaesthetised over the aseptically prepared jugular vein site and a 16G x 2' catheter used.