Virbaxyl 10% is given by slow intravenous injection. Dosage depends upon the degree of sedation required and the response of the animal, and is 0.5–1 ml/100 kg bodyweight. Animals do not usually become recumbent with Virbaxyl 10% and light to deep sedation with variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. Virbaxyl 10% may be employed as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia. Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate.