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Date: Tuesday, April 23, 2024 15:20

Description: Bimeda logo
Release 3.36
Dectospot 10 mg/ml Spot-on Solution for Cattle and Sheep
 
Species: Sheep, Cattle
Therapeutic indication: Pharmaceuticals: Ectoparasiticides: For cattle, For sheep
Active ingredient: Deltamethrin
Product:Dectospot 10 mg/ml Spot-on Solution for Cattle and Sheep
Product index: Dectospot 10 mg/ml Spot-on Solution for Cattle and Sheep
Cattle - milk: Zero hours
Cattle - meat: 17 days
Sheep - meat: 35 days
Withdrawal notes: Not for use in ewes producing milk for human consumption
Incorporating:
Qualitative and quantitative composition
Active Substance: Deltamethrin 10mg/ml.
Pharmaceutical form
Spot-on Solution.
A clear pale gold oily liquid.
Clinical particulars
Target species
Cattle and sheep.
Indications for use
As a topical application for the control of lice and flies on cattle; ticks, lice, keds and established blowfly strike on sheep and lice and ticks on lambs.
On cattle: for the control of both sucking and biting lice, including Bovicola (Damalinia) bovis, Solenopotes capillatus, Linognathus vituli and Haematopinus eurysternus on all ages of cattle including dairy cattle producing milk for human consumption. Also as an aid in the control of both biting and nuisance flies including Haematobia irritans, Stomoxys calcitrans, Musca species and Hydrotaea irritans.
On sheep: For the control of ticks Ixodes ricinus and of lice and keds and established blowfly strike.
On lambs: For the control of ticks Ixodes ricinus and lice Bovicola ovis.
Contra-indications
None.
Special warnings for each target species
Care should be taken to avoid inaccurate dosing, misadministration or too frequent and repeated use of ectoparasiticides from the same class over an extended period of time as these practices increase the risk of development of resistance and could ultimately result in ineffective therapy.
Special precautions for use
i) Special precautions for use in animals
For external use only.
ii) Special Precautions to be taken by the person administering the product to animals
Wear protective clothing including waterproof apron and boots and impervious gloves when either applying the product or handling recently treated animals.
Remove heavily contaminated clothing immediately and wash before use.
Wash splashes from skin immediately with soap and plenty of water.
Wash hands and exposed skin after handling this product and before meals.
In case of contact with eyes, rinse immediately with plenty of clean, running water and seek medical advice.
In case of accidental ingestion, wash out mouth immediately with plenty of water and seek medical advice.
Do not smoke, drink or eat while handling the product.
This product contains deltamethrin which may produce tingling, itchiness and blotchy redness on exposed skin. If you feel unwell after working with this product, consult your doctor and show this label.
Advice to medical practitioners: Advice on clinical management is available from the National Poisons Information Service.
Adverse reactions
Minor signs of discomfort have been seen in some cattle during the 48 hours after treatment. This is of no long term detriment to the animal.
Use during pregnancy, lactation or lay
No special precautions are recommended and the product can therefore be used in pregnancy.
Interactions
Some organo-phosphorous insecticides can reduce metabolism rate and thus enhance deltamethrin toxicity. Do not mix any other insecticide or acaricide with Dectospot Spot-on Solution.
Amounts to be administered and administration route
The product should be applied using an appropriate application device:
-For the 250ml and 500ml presentations a graduated chamber attached to the container is used.
-For the 1 litre and 2.5 litre presentations it is recommended to use an appropriate applicator.
The recommended use of the application devices is illustrated below.
1. Use of the graduated chamber on the 250ml and 500 ml containers:
Description: h-982
2.Attaching the 1 and 2.5 litre containers to the recommended applicator:
Description: h-983
Dose:
Cattle:10 ml
Sheep: 5ml
Lambs (under 10 kg bodyweight or 1 month of age): 2.5ml
Administration: Apply a single dose with the special dispenser pack or the Dectospot Applicator on one spot on the mid-line of the back at the shoulders as directed on dispenser or applicator gun pack. For blowfly strike on sheep, see following specific indication directions.
Description: h-984
Lice on cattle: One application will generally eradicate all lice. Complete clearance of all lice may take 4 - 5 weeks during which time lice hatch from the eggs and are killed. A very few lice may survive on a small minority of animals. Therefore, it may be necessary on rare occasions to re-treat an animal 6 - 8 weeks later.
Flies on cattle: To control biting and non-biting flies, frequency of treatment will depend on the numbers and species of flies present. Where horn-flies predominate, good control can be expected for 4 - 8 weeks. Treatment for fly control should not be repeated within four weeks.
Ticks on sheep: Application to the mid-point of the shoulders will provide useful control of ticks attaching to animals of all ages, for up to 6 weeks after treatment.
Keds and lice on sheep: Application to the mid-point of the shoulders of sheep in short or long fleece will reduce the incidence of a biting louse or ked infestation over a 4 - 6 week period after treatment.
N.B. For control of ticks, keds and lice on sheep, the fleece should be parted and Spot On applied to the skin of the animal.
When using the Dectospot applicator application to the skin can be achieved by inserting the T bar to separate the fleece and penetrate down to the skin level before squeezing the applicator handle.
Established blowfly strike on sheep: Apply directly to the maggot infected area as soon as the fly strike is seen. One application will ensure blowfly larvae are killed in a short time. Clipping out of stained wool before treatment is advisable.
Lice and ticks on lambs: Application to the mid-point of the shoulders will provide useful control of ticks for up to 6 weeks after treatment, and will reduce the incidence of biting lice over a 4-6 week period after treatment.
Overdose
There are no specific recommendations in the case of overdosage.
Withdrawal periods
Cattle (meat) – 17 days
Cattle (milk) – zero hours
Sheep (meat) – 35 days
Pharmacological particulars
ATCvet code: QP53AC11
Pharmacotherapeutic group: Ectoparasiticides, insecticides and repellents. Pyrethrins and pyrethroids.
Pharmacodynamic properties
Deltamethrin is a synthetic pyrethroid possessing pesticidal activity. It is one of a large family of pyrethroid esters which have evolved as synthetic analogues of the original insecticidal extracts isolated from powdered pyrethrum flowers.
Deltamethrin is an alpha-cyano pyrethroid and is a member of the second generation of pyrethroids in which the overall stability of the molecule is improved with correspondingly increased resistance to photo- and bio- degredation and enhanced insecticidal activity. It is more potently toxic to insects and acarines because of the slower rate of metabolism.
Pharmacokinetic properties
The precise mode of insectical activity of pyrethroids remains uncertain, but they are potent neurotoxins in insects, causing failure in sensory coordination and disorganised motor activity, hence the 'knock-down' effect. Pyrethroids are metabolised through oxidative and neurotoxic pathways far more rapidly in mammals, so that neurotoxic effects can only occur at dosages which are many orders of magnitude greater than those required from pesticidal activity.
Environmental properties
Deltamethrin has the potential to adversely affect non-target organisms, both in water and in dung. Following treatment, excretion of potentially toxic levels of deltamethrin may take place over a period of 2 to 4 weeks. Faeces containing deltamethrin excreted onto pasture by treated animals may reduce the abundance of dung feeding organisms which may impact on the dung degredation.
Deltamethrin is very toxic to dung fauna, aquatic organisms and honey bees, is persistent in soils and may accumulate in sediments.
Pharmaceutical particulars
List of excipients
Triglycerides, medium chain
Incompatibilities
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf-Life
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf-life after first opening the immediate packaging: 3 months
Special Precautions for Storage
The veterinary medicinal product does not require any special temperature storage conditions. Keep the container in the outer carton in order to protect from light .
Store in tightly closed original container away from food, drink and animal feeding stuffs.
Nature and Contents of Immediate Packaging
250 and 500 ml natural high-density polyethylene bottle with internal graduated calibration chamber with black plastic heat-sealed screw cap.
1 litre and 2.5 litre white high density polyethylene flexipack with white polypropylene closures and induction heat-sealed screw-cap and spouted cap for connection to applicator.
Not all pack sizes may be marketed.
Special precautions for the disposal of unused veterinary medicinal product or waste material derived from the use of such products.
Dangerous to fish and other aquatic life. Do not contaminate ponds, waterways or ditches with the product or used container.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Marketing Authorisation Number
Vm 50146/4023
Significant changes
Date of the first authorisation or date of renewal
Date of Revision of the Text
February 2020
Any other information
Nil.
Legal category
Legal category: POM-VPS
GTIN
GTIN description:Dectospot 10 mg/ml Spot-on Solution for Cattle and Sheep: 2 x 2.5 litre value pack
GTIN:5391510234777
GTIN description:Dectospot 10 mg/ml Spot-on Solution for Cattle and Sheep: 1 litre
GTIN:5391510233992