Each ml contains

Cypermethrin High:Cis (80:20) 12.5 mg

Clear, blue, non-aqueous pour-on solution.

Sheep.

For the treatment and control of headflies, and treatment of ticks and biting lice. For the prevention and treatment of blowfly strike.

Not to be used in lambs less than one week old.

For the prevention of blowfly strike; do not administer to animals of less than 12.5 kg bodyweight.

Avoid treating very young lambs if the weather is unseasonably hot.

Do not use in the case of hypersensitivity to the active substance or to any of the excipients.

Frequent and repeated use of antiparasiticides from the same class may increase the risk of development to resistance.

Care must be taken not to apply the product right to the lamb’s tail, as a ewe recognises a young lamb partly by the smell of the tail area.

Blowflies are attracted by dirty, damp wool or open wounds. The more common site for fly strike is the rump due to soiling caused by diarrhoea and urine staining. The efficacy of the product is reduced in the presence of soiled or dirty wool. Therefore, sheep must be dagged (crutched) regularly and appropriate worm control measures employed.

Take care not to apply product in the sheep’s eyes. This precaution should be observed particularly when treating breeds with little wool on their heads.

Full operating and maintenance instructions, including details on the use of nozzles are supplied with each applicator gun. Please read carefully before use. Maintain applicator gun carefully to ensure accurate dosage.

For external use only.

This product may also cause hypersensitivity reactions.

Avoid skin and/or eye contact.

Avoid children from getting access to the product or treated animals.

Use in a well-ventilated area and avoid inhaling the vapour.

Wear eye protection, protective clothing, rubber gloves and boots when applying the product and handling the animal until the product has dried.

Wear a disposable face-mask when applying as a fan-spray for the prevention of blowfly-strike.

Make sure when attaching the recommended applicator gun onto the container that the coiled retainer is secured onto the cap and the applicator.

Wash splashes from skin and eyes immediately with plenty of clean water.

If irritation persists seek medical advice immediately and show the package leaflet to the physician.

Remove contaminated clothing immediately and wash exposed skin with plenty of clean water.

Do not eat, drink or smoke whilst using the product. Wash hands immediately after use.

In case of accidental ingestion or mouth contact, immediately rinse the mouth with plenty of water and seek medical advice.

Cypermethrin is extremely toxic to aquatic and dung organisms As a precautionary measure sheep must be kept away from watercourses for at least 12 hours following treatment (see section 5.3, ‘Environmental properties’). Given the risks to the environment the use of the product should be limited to one treatment per year per pasture. Long term effects on dung insects caused by continuous or repeated use of pyrethroid ectoparasiticides cannot be excluded. Therefore repeated treatment of animals on the same pasture with a pyrethroid-containing product within a season should only be given in the absence of alternative treatments or approaches to maintain animal/flock health, as advised by a veterinarian

None known.

Can be used during pregnancy. Pregnant ewes must be handled with care. See section 'Withdrawal Periods'.

The product must be applied only with the recommended applicator gun, as the product may have a detrimental effect on certain components of conventional dosing guns.

To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked. On completion of each treatment cycle of the product and before the dosing gun is stored, immediately expel any remaining product in the dosing gun.

Administer by means of the recommended applicator gun as follows:

Apply as a fan-spray to the surface of the fleece on the back and hindquarters of the sheep using the applicator gun fitted with the blue fan-spray nozzle. Half the dose should be applied to the shoulders, back and flanks, and half to the rump. The distance between the nozzle and the fleece should be approximately 20 cm. Each dose will require 2 or 3 sweeps to apply. THE PRODUCT WILL PREVENT BLOWFLY STRIKE ONLY ON AREAS COVERED BY SPRAY. One application will give 6-8 weeks protection.

Apply directly to all the affected parts at the rate of 2.5 ml per 100 –150 cm2 . The Red T-bar nozzle should be used. Most strikes will require 5-10 ml. Ensure that all affected parts are treated. A single application is sufficient to ensure that larvae are expelled and killed within a few hours.

SEE FIGURE 2 Below

Dosage: 5 ml per 20 kg bodyweight up to a maximum of 20 ml.

Using the green straight nozzle on the applicator gun, apply as a pin-stream from the shoulders to the rump along the middle of the backline.

Sheep may be treated off-shears or at any time during the year.

SEE FIGURE 3 Below

Dosage: Adult sheep and lambs greater than 10 kg: 10 ml per 20 kg bodyweight, up to a maximum of 40 ml. Lambs under 10 kg: 5 ml followed 3 weeks later by a 10 ml application.

Using the green straight nozzle on the Pour-On Gun, apply as a pin-stream from the crown of the head to the top of the rump.

See FIGURE 4 Below

Dose: 5 ml per animal irrespective of size.

Apply to the top of the head between the ears using the T-bar nozzle.

Take care not to apply product in the sheep’s eyes.

One application before the start of the headfly season will give up to 4 weeks protection. Re-treat as required.

This product contains a dye to aid in the identification of treated animals. The colour is temporary and will fade from the fleece within 48 hours of application.

Toxic signs in mammals are tremors, hyperexcitability, salivation, choreoathetosis and paralysis, rarely leading to death. Usually, the signs disappear rapidly and the animals recover, generally within a week.

There is no specific antidote but symptomatic therapy can be given if considered necessary.

Meat and offal: 8 days.

Milk: 5 days

Pharmacotherapeutic group: ectoparasiticides for topical use, incl. Insecticides. ATC vet code: QP53AC08.

Pharmacodynamic properties

Cypermethrin is a neuropoison acting on the axons in the peripheral and central nervous system of insects by interacting with sodium channels.

Pharmacokinetic particulars

Synthetic pyrethroids are generally metabolised in mammals through ester hydrolysis, oxidation and conjugation and there is no tendency to accumulate in tissues.

Cypermethrin is moderately persistent and non-mobile in soil. It is extremely toxic to aquatic invertebrates. Cypermethrin is toxic to dung insects and to honey bees. Long term effects on dung insects caused by continuous or repeated use of the product cannot be excluded.

List of Excipients

Green S Dye (E142)
Diethylene glycol monobutyl ether

None known.

Shelf life of the veterinary medicinal product as packaged for sale: 2 years

Shelf life after first opening of the immediate packaging: 3 months.

Special precautions for storage:Store away from food, drink and animal feeding stuffs.

Do not store above 25°C. Protect from direct sunlight. Store in tightly closed original container.

White high-density polyethylene flat bottom containers with polypropylene closures and induction heat-sealed wadding, at 2.5 litre and 5 litre pack sizes.

Not all pack sizes may be marketed.

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

EXTREMELY DANGEROUS to aquatic invertebrates. Do not contaminate ponds, waterways or ditches with the product or empty container.

5 April 2011

October 2018

Nil