Do not use in cases of hypersensitivity to the active susbstances or to any of the excipients.
Do not use in non-lactating cattle.
Do not use in the case of known resistance of cefalexin and/or kanamycin.
Special precautions for safe use in the target species:
The veterinary medicinal product should be used for treatment of clinical mastitis only.
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional and farm level) epidemiological information about susceptibility of the target bacteria as well as by taking into account official national antimicrobial policies. Inappropriate use of the veterinary medicinal product may increase the prevalence of bacteria resistant to cefalexin and kanamycin and may decrease the effectiveness of treatment with other cephalosporins or aminoglycosides due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious. People with known hypersensitivity to cefalexin and kanamycin should avoid contact with the veterinary medicinal product.
Take all recommended precautions. Handle this veterinary medicinal product with great care to avoid exposure by accidental contact with the skin. Personal protective equipment consisting of gloves should be worn when handling the veterinary medicinal product. Wash exposed skin after use.
If you develop symptoms following exposure, such as skin rash, you should seek medical advice and show the package leaflet or the label to the physician. Swelling of the face, lips and eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.
Use during pregnancy, lactation or lay
Pregnancy and lactation:
Laboratory studies in animals have not produced any evidence of teratogenic effects. Field studies in dairy cows have not produced any evidence of a teratogenic, foetotoxic or maternotoxic effect. Can be used during pregnancy. Can be used during lactation.
Interaction with other medicinal products and other forms of interaction
In general, combination with bacteriostatic antimicrobials should be avoided. In case of resistance to cefalexin, cross-resistance with other cephalosporins is likely to occur. In case of resistance to kanamycin, cross-resistance occurs between kanamycin, neomycin and paromomycin. A one way resistance with streptomycin is known.
Withdrawal periods
Meat and offal: 10 days.
Milk: 5 days.