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Dosage and administration
Horse: Intravenous use
Dog: Intravenous, subcutaneous and intramuscular use
Cat: Intravenous and subcutaneous use
HORSE
As an analgesic
Monotherapy:
0.1 mg/kg (1 ml/100 kg bw) IV.
As a sedative and as a pre-anaesthetic
With detomidine:
Detomidine: 0.012 mg/kg IV, followed within 5 minutes by
Butorphanol: 0.025 mg/kg (0.25 ml /100 kg bw) IV.
With romifidine:
Romifidine: 0.05 mg/kg IV, followed within 5 minutes by
Butorphanol: 0.02 mg/kg (0.2 ml/100 kg bw) IV.
With xylazine:
Xylazine: 0.5 mg/kg IV, followed after 3-5 minutes by
Butorphanol: 0.05–0.1 mg/kg (0.5-1 ml/100 kg bw) IV.
DOG
As an analgesic
Monotherapy:
0.1 - 0.4 mg/kg (0.01 – 0.04 ml/kg bw) slowly IV (in the lower to medium dose range) as well as IM, SC.
For post-operative pain control the injection should be administered 15 minutes before the end of anaesthesia in order to achieve sufficient pain relief during the recovery phase.
As a sedative
With medetomidine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IV, IM
Medetomidine: 0.01 mg/kg IV, IM.
As a pre-anaesthetic
With medetomidine and ketamine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IM
Medetomidine: 0.025 mg/kg IM, followed after 15 minutes by
Ketamine: 5 mg/kg IM.
It is only possible to use atipamezole 0.1 mg/kg body weight for medetomidine-antagonisation when ketamine action has ceased.
CAT
As an analgesic
Monotherapy:
15 minutes prior to recovery either: 0.4 mg/kg (0.04 ml/kg bw) SC or: 0.1 mg/kg (0.01 ml/kg bw) IV
As a sedative
With medetomidine:
Butorphanol: 0.4 mg/kg (0.04 ml/kg bw) SC
Medetomidine: 0.05 mg/kg SC.
For wound debridement an additional local anaesthesia is recommended.
Medetomidine-antagonisation is possible with atipamezole 0.125 mg/kg body weight.
As a pre-anaesthetic
With medetomidine and ketamine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IV
Medetomidine: 0.04 mg/kg IV
Ketamine: 1.5 mg/kg IV.
It is only possible to use atipamezole 0.1 mg/kg body weight for medetomidine–antagonisation when ketamine action has ceased.
Butorphanol is intended for use where short (horse and dog) and short to medium (cat) analgesia is required. The dose may be repeated as required. The need for and timing of repeated treatment will be based on clinical response. For information on the duration of analgesia see section “Further information”.
Rapid intravenous injection should be avoided.
The stopper must not be punctured more than 25 times.
Do not mix the product with other veterinary medicinal products in one syringe.