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Date: Wednesday, May 22, 2024 18:49

Release 2.60
Canidryl 20mg and 100mg Tablets for Dogs
 
Species: Dogs
Therapeutic indication: Pharmaceuticals: Anti-inflammatory preparations: Oral: Other NSAIDs
Active ingredient: Carprofen
Product:Canidryl 20mg Tablets for Dogs
Canidryl 100mg Tablets for Dogs
Product index: Canidryl Tablets for Dogs
Incorporating:
Qualitative and quantitative composition
Each grilled meat flavoured tablet contains Carprofen 20 mg/tablet or 100mg/tablet
Pharmaceutical form
Grilled meat flavoured tablets.
20 mg: A plain round flat bevelled edge white tablet with a breakline on one side. The tablets can be broken into equal halves.
100 mg: A white to off white round shape tablets with a cross break line on one side. The tablets can be divided into halves or quarters.
Clinical particulars
Target Species
Dogs
Indications for Use
Reduction of inflammation and pain caused by musculo-skeletal disorders and degenerative joint disease. As a follow up to parenteral analgesia in the management of post-operative pain for soft tissue surgery.
Contra-indications
Do not use in cats. Do not use in case of hypersensitivity to active substance or to any of the excipients. Do not use in dogs suffering from cardiac, hepatic or renal disease, where there is a possibility of gastro-intestinal ulceration or bleeding, or where there is evidence of a blood dyscrasia.
Special Precautions for use in Animals
Use in dogs less than 6 weeks of age, or in aged dogs, may involve additional risk. If such a use cannot be avoided, dogs may require careful clinical management. Avoid use in any dehydrated, hypovolaemic or hypotensive dog, as there is a potential risk of increased renal toxicity.
Concurrent administration of potential nephrotoxic drugs should be avoided. NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated.
Do not administer other NSAIDs concurrently or within 24 hours of each other. Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs, which can lead to toxic effects.
User warnings
In the event of accidental ingestion of the tablets, seek medical advice and show the doctor the package leaflet. Wash hands after handling the product.
Adverse reactions (Frequency and Seriousness)
Typical undesirable effects associated with NSAIDs, such as vomiting, soft faeces/diarrhoea, faecal occult blood, loss of appetite and lethargy have been reported. These adverse reactions occur generally within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal. If adverse reactions occur, use of the product should be stopped and the advice of a veterinarian should be sought. As with other NSAIDs there is a risk of rare renal or idiosyncratic hepatic adverse events.
Use During Pregnancy, lactation or lay
Studies in laboratory species (rat and rabbit) have shown evidence of foetotoxic effects of carprofen at doses close to the therapeutic dose. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Do not use in pregnant or lactating bitches.
Interaction with other medicinal products and other forms of interaction
Carprofen must not be administered with glucocorticoids. Refer also to "Special Precautions for Use".
Amounts to be administered and administration route
For oral administration. 4 mg carprofen per kg bodyweight per day. An initial dose of 4 mg carprofen per kg bodyweight per day given as a single daily dose or in two equally divided doses may, subject to clinical response, be reduced after 7 days to 2 mg carprofen/kg bodyweight/day given as a single dose. Duration of treatment will be dependant upon the response seen. Long term treatment should be under regular veterinary supervision. To extend analgesic and anti-inflammatory cover post-operatively, parenteral preoperative treatment may be followed with Carprofen tablets at 4mg/kg/day for 2 days. Do not exceed the stated dose.
Return any divided tablets to the blister pack or container and use within 72 hours. Divided tablets should be used at the next administration. Any divided tablets remaining after the last administration of the product should be discarded.
Overdose (symptoms, emergency procedures, antidotes)
No signs of toxicity appeared when dogs were treated with Carprofen at levels up to 6 mg/kg twice daily for 7 days (3 times the recommended dose rate of 4mg/kg) and 6mg/kg once daily for a further 7 days (1.5 the recommended dose rate of 4 mg/kg). There is no specific antidote for carprofen overdosage but general supportive therapy, as applied to clinical overdosage with NSAIDs should be applied.
Pharmaceutical particulars
Canidryl 20mg tablets:
Shelf-life when packed in blister packs: 4 years
Shelf-life when packed in HDPE containers: 3 years
Canidryl 100mg Tablets
Shelf-life: 3 years.
Return any divided tablets to the blister pack or container and use within 72 hours.
Store in a dry place in the original package. Protect from light.
Pack sizes
Pack sizes for Blister Packs
6, 10, 14, 20, 28, 30, 42, 50, 56, 60, 70, 84, 98, 100, 140, 180, 200, 250, 280, 300, 500 and 1000 tablets.
Pack sizes for Containers
The container pack sizes are as follows:
6, 10, 14, 20, 28, 30, 42, 50, 60 ,70, 84, 98, 100, 140, 180, 200, 250, 280, 300, 500, 1000
Not all pack sizes may be marketed.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Marketing Authorisation Number
Canidryl 20mg - Vm 08749/4009
Canidryl 100mg - Vm 08749/4011
Significant changes
Legal category
Legal category: POM-V