Medetor is intended for:
Dogs: Intramuscular or intravenous injection.
Cats: Intramuscular injection.
Dogs
For sedation the product should be administered at the rate of 750 μg medetomidine hydrochloride i.v. or 1000 μg medetomidine hydrochloride i.m. per square meter of body surface. Use the table below to determine the correct dosage on the basis of body weight:
Maximal effect is obtained within 15-20 minutes. Clinical effect is dose-dependent, lasting from 30 – 180 minutes.
| i.v. injection | i.m. injection |
Body weight (kg) | Medetor [ml/dog] | corresp. to Med [μg/kg bw] | Medetor [ml/dog] | corresp. to Med. [μg/kg bw] |
1 2 3 4 5 6 7 8 9 10 12 14 16 18 20 25 30 35 40 50 60 70 80 90 100 | 0.08 0.12 0.16 0.19 0.22 0.25 0.28 0.30 0.33 0.35 0.40 0.44 0.48 0.52 0.56 0.65 0.73 0.81 0.89 1.03 1.16 1.29 1.41 1.52 1.63 | 80.0 60.0 53.3 47.5 44.0 41.7 40.0 37.5 36.7 35.0 33.3 31.4 30.0 28.9 28.0 26.0 24.3 23.1 22.2 20.6 19.3 18.4 17.6 16.9 16.3 | 0.10 0.16 0.21 0.25 0.30 0.33 0.37 0.40 0.44 0.47 0.53 0.59 0.64 0.69 0.74 0.86 0.98 1.08 1.18 1.37 1.55 1.72 1.88 2.03 2.18 | 100.0 80.0 70.0 62.5 60.0 55.0 52.9 50.0 48.9 47.0 44.2 42.1 40.0 38.3 37.0 34.4 32.7 30.9 29.5 27.4 25.8 24.6 23.5 22.6 21.8 |
For premedication:
10-40 µg medetomidine hydrochloride per kg body weight, corresponding to 0.1-0.4 ml per 10 kg body weight. The exact dose depends on the combination of drugs used and the dosage(s) of the other drug(s). The dose should furthermore be adjusted to the type of surgery, length of procedure and patient temperament and weight. Premedication with medetomidine will significantly reduce the dosage of the induction agent required and will reduce volatile anaesthetic requirements for maintenance anaesthesia. All anaesthetic agents used for induction or maintenance of anaesthesia should be administered to effect. Before using any combinations, product literature for the other products should be observed. See also 'special precautions.'
Cats
For moderate-deep sedation and restraint of cats Medetor should be administered at a dosage of 50 – 150 μg medetomidine hydrochloride / kg bw (corresp. to 0.05 – 0.15 ml Medetor / kg bw).
For anaesthesia Medetor should be administered at a dosage of 80 μg medetomidine hydrochloride / kg bw (corresp. to 0.08 ml Medetor / kg bw).and 2.5 to 7.5 mg ketamine / kg bw. Using this dosage anaesthesia occurs within 3 – 4 minutes and is apparent for 20 – 50 minutes. For longer lasting procedures administration has to be repeated by using ½ of the initial dose (i.e. 40 μg medetomidine hydrochloride (corresp. to 0.04 ml Medetor / kg bw).and 2.5 - 3.75 mg ketamine / kg bw) or 3.0 mg ketamine / kg bw alone. Alternatively, for longer lasting procedures anaesthesia may be extended by use of the inhalation agents isoflurane or halothane, with oxygen or oxygen/nitrous oxide.