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Date: Wednesday, April 24, 2024 15:14

Description: Dechra
Release 4.65
Vitbee® Solution for Injection
 
Species: Cattle, Horses and other equidae, Sheep
Therapeutic indication: Pharmaceuticals: Dietary supplements and fluid metabolites: Vitamin preparations - injectable
Active ingredient: Cyanocobalamin (Vit B12)
Product:Vitbee® Solution for Injection
Product index: Vitbee Solution for Injection
Cattle - milk: Zero hours
Cattle - meat: Zero days
Sheep - meat: See notes
Withdrawal notes: Vitbee 250: Sheep; zero days: Horse & Foal meat: zero days/Vitbee 1000: Horse & Foal meat: zero days
Incorporating:
Qualitative and quantitative composition
Vitbee 250, 0.025% w/v solution for injection:
Contains: Active substance:
Cyanocobalamin 0.025% w/v
Excipient: Phenol 0.500% w/v
Vitbee 1000, 0.100% w/v solution for injection:
Contains: Active substance:
Cyanocobalamin 0.100% w/v
Excipient: Phenol 0.500% w/v
Pharmaceutical form
Solution for injection. A clear, red, sterile solution for injection.
Clinical particulars
Target species
Vitbee 250, 0.025% w/v solution for injection:
Sheep, foals and calves.
Vitbee 1000, 0.100% w/v solution for injection:
Cattle and horses, calves and foals.
Indications for use
Vitbee 250, 0.025% w/v solution for injection:
An aid in raising vitamin B12 levels in sheep, foals and calves.
For use in the treatment of vitamin B12 deficiency, and for poor growth rates and general unthriftiness in young animals when associated with the above deficiency.
Vitbee 1000, 0.100% w/v solution for injection:
An aid in raising vitamin B12 levels in cattle and horses, calves and foals.
For use in the treatment of vitamin B12 deficiency, and for poor growth rates and general unthriftiness in young animals when associated with the above deficiency.
Contraindications
Do not give by the intravenous route.
Special precautions for use in animals
Observe normal aseptic precautions.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Care should be taken to avoid accidental self-injection or ingestion. In the case of accidental self-injection or ingestion, seek medical advice as a precautionary measure.
Following skin/eye contamination, wash/irrigate area thoroughly with cold water. Seek medical attention if irritation persists.
Wash hands after use.
Use during pregnancy and lactation
Not contraindicated in pregnant or lactating animals.
Amounts to be administered and administration route
Vitbee 250, 0.025% w/v solution for injection:
Sheep: 1-3 ml
Calves and foals: 2-4 ml
By intramuscular or subcutaneous injection. Repeat in 7 days if required. Following treatment, the vitamin B12 status of herbivores should be maintained by dietary supplementation with cobalt.
Vitbee 1000, 0.100% w/v solution for injection:
Cattle and horses: 1-3 ml
Calves and foals: 0.5-1 ml
By intramuscular or subcutaneous injection. Repeat in 7 days if required. Following treatment, the vitamin B12 status of herbivores should be maintained by dietary supplementation with cobalt.
Overdose
Overdosage is unlikely.
Withdrawal periods
Meat: zero days; Milk: zero hours.
Pharmacological particulars
Pharmacotherapeutic group: Cyanocobalamin
ATCvet code: QB03BA01
Pharmacodynamic properties
B vitamins are not stored in the body to any great extent.
Pharmacokinetic properties
The metabolism of cyanocobalamin is complex and is associated closely with that of folic acid and of ascorbic acid. It is important for maintenance of normal haemopoiesis, protection of the liver, maintenance of muscle tissue, healthy skin, brain and pancreatic metabolism.
Pharmaceutical particulars
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening the immediate packaging: 28 days.
Special precautions for storage
Do not store above 25°C.
Protect from light.
Following withdrawal of the first dose, use the product within 28 days.
Immediate packaging
50 ml type I amber glass vial, fitted with a red type I bung and aluminium overseal.
Secondary packaging: cardboard carton.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Marketing Authorisation Holder (if different from distributor)
Alfasan Nederland BV, Kuipersweg 9, 3449 JA Woerden, The Netherlands.
Marketing Authorisation Number
Vm 36408/4011: 250
Vm 36408/4012: 1000
Significant changes
Date of the first authorisation or date of renewal
26 February 1993
Date of revision of the text
August 2021
Any other information
For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.
Legal category
Legal category: POM-VPS
GTIN
GTIN description:Vitbee 250, 0.025% w/v Solution for Injection:
GTIN:05055031419289
GTIN description:Vitbee 1000, 0.100% w/v Solution for Injection:
GTIN:05055031419296