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Dosage and administration
For use in drinking water.
The dose is 25 mg tylvalosin per kg bodyweight per day in drinking water for 3 consecutive days.
Determine the combined bodyweight (in kg) of all the birds to be treated. For example, one sachet of 40 g is sufficient to treat a total of 1,000 birds with an average bodyweight of 1 kg; one sachet of 400 g is sufficient to treat a total of 10,000 birds with an average bodyweight of 1 kg. In order to achieve a correct dose, the preparation of a concentrated (stock) solution might be required (e.g. to treat a total of 500 kg total bird weight, only 50% of the prepared stock solution prepared from the 40 g sachet should be used).
The veterinary medicinal product should be added to a volume of water that the birds will consume in one day. The intake of medicated water depends on the clinical condition of the animals. In order to obtain the correct dose the concentration of Aivlosin has to be adjusted accordingly.
No other source of drinking water should be available during the medication period.
Mixing instructions
The veterinary medicinal product may be mixed directly into the drinking water system or first mixed as a stock solution into a smaller amount of water, which is then added into the drinking water system.
When mixing the veterinary medicinal product directly into the drinking water system, the contents of the sachet should be sprinkled onto the surface of the water and mixed thoroughly until a clear solution is produced (usually within 3 minutes).
When preparing a stock solution, the maximum concentration should be 40 g of product per 1,500 ml of water and it is necessary to mix the solution for 10 minutes. After this time, any remaining cloudiness will not affect efficacy of the product.
Only a sufficient amount of medicated drinking water should be prepared to cover the daily requirements.
Medicated drinking water should be replaced every 24 hours.
No signs of intolerance have been observed in poultry species at up to 150 mg tylvalosin per kg bodyweight per day for 5 days.