Calculations to achieve the correct dose rate and achieve the correct inclusion rate should be based on:Inclusion rate (ppm)=dose rate(mg/kg bwt) x bodyweight (kg)/daily feed intake(kg).
To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
The intake of medicated feed depends on the clinical condition of the animals. In order to obtain the correct dosage the concentration of tiamulin hydrogen fumarate has to be adjusted accordingly.
Pigs
Treatment of swine dysentery caused by B. hyodysenteriae, treatment of porcine colonic spirochaetosis (colitis) caused by B. pilosicoli.
Dosage: 5-10 mg tiamulin hydrogen fumarate/kg bodyweight daily administered for 7 to 10 consecutive days. The dosage will normally be achieved by an inclusion level of 100-200 ppm tiamulin hydrogen fumarate in the finished feed provided that feed intake is unaffected.
Amount of THF (mg/g) per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.125 - 0.25 kg |
Prevention of swine dysentery caused by B. hyodysenteriae.
Dosage: 2.0 mg tiamulin hydrogen fumarate/kg bodyweight daily. The dosage will normally be achieved by an inclusion level of 40 ppm tiamulin hydrogen fumarate in the finished feed, providing feed intake is unaffected. Preventive medication with tiamulin should be given for 2-4 weeks.
Preventative treatment with tiamulin should only be initiated after confirmed infection with B. hyodysenteriae and then as part of a program including measures aiming to eradicate or control the infection in the herd.
Amount of TH (mg/g) per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.05 kg |
Treatment of porcine proliferative enteropathy (ileitis) caused by L. intracellularis.
Dosage: 7.5 mg tiamulin hydrogen fumarate/kg bodyweight daily administered for 10 to 14 consecutive days. The dosage will normally be achieved by an inclusion level of 150 ppm tiamulin hydrogen fumarate in the finished feed providing that feed intake is unaffected.
Amount of THF (mg/g) per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.188 kg |
Treatment of enzootic pneumonia caused by M. hyopneumoniae.
Dosage: 5.0-10.0 mg tiamulin hydrogen fumarate/kg bodyweight daily administered for 7 to 10 consecutive days. The dosage will normally be achieved by an inclusion level of 100-200 ppm tiamulin hydrogen fumarate in the finished feed provided that feed intake is unaffected.
Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication.
Amount of THF (mg/g per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.125 - 0.25 kg |
Chickens (broiler, replacement pullet, laying and breeding hens)
Treatment and prevention of chronic respiratory disease (CRD) caused by M. gallisepticum and airsacculitis and infectious synovitis caused by M. synoviae.
Dosage - Treatment and prevention: 25 mg tiamulin hydrogen fumarate/kg bodyweight daily administered for the period of 3 to 5 consecutive days. This is normally achieved by an inclusion level of 250-500 ppm tiamulin hydrogen fumarate in finished feed provided that feed intake is unaffected. Inclusion levels in the higher range will in most cases be needed to avoid underdosing. In fast growing birds, e.g. broiler chickens during the first 2-4 weeks of life, inclusion levels in the lower range may be sufficient.
Amount of THF (mg/g) per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.313 - 0.625 kg |
Turkeys (young poults, breeding turkeys)
Treatment and prevention of infectious sinusitis and airsacculitis caused by M. gallisepticum, M. synoviae and M. meleagridis.
Dosage - Treatment and prevention: 40 mg tiamulin hydrogen fumarate/kg bodyweight daily administered for the period of 3 to 5 consecutive days. This is normally achieved by an inclusion level of 250-500 ppm tiamulin hydrogen fumarate in finished feed provided that feed intake is unaffected. Inclusion levels in the higher range will be in most cases be needed to avoid underdosing. In fast growing birds, e.g. poults during the first 2-4 weeks of life, inclusion levels in the lower range may be sufficient.
Amount of THF (mg/g) per premix formulation | Amount of premix formulation per one tonne of feed |
800.0 | 0.313 - 0.625 kg |
Preventative treatment with tiamulin should only be initiated after confirmed infection with M. gallisepticum, M. synoviae and M. meleagridis and then as an aid in the prevention strategy to reduce the clincial signs and mortality from respiratory disease in flocks where infection in ovum is likely because the disease is known to exist in the parent generation. The prevention strategy should include efforts to eliminate the infection from the parent generation.
Use during pregnancy, lactation or lay
Can be used in pigs during pregnancy and lactation.
Can be used in laying and breeding chickens and turkeys.