Target species
Species: cattle from 2 months of age.
Indications for use
To reduce the clinical signs and lung lesions caused by Mannheimia haemolytica serotype A1 and Histophilus somni in calves from 2 months of age.
Onset of Immunity:
3 weeks.
Contra-indications
Do not vaccinate unhealthy animals.
Do not use in case of hypersensitivity to the active substances, to the adjuvant or to any of the excipients.
Special warnings for each target species
None
Special precautions for use
Special precautions for use in animals
Do not use in animals which are underweight for their age.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
To the user:
This veterinary medicinal product contains mineral oil. Accidental injection/self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.
If you are accidentally injected with this veterinary medicinal product, seek prompt medical advice even if only a very small amount is injected and take the package leaflet with you.
If pain persists for more than 12 hours after medical examination, seek medical advice again.
To the physician:
This product contains mineral oil. Even if small amounts have been injected, accidental injection with this veterinary medicinal product can cause intense swelling, which may, for example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT, surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.
Adverse reactions
Very common: A transient rise in temperature (up to 2 ºC) after each vaccination can occur but this resolves after 4 days. Vaccinated animals might show a local swelling at the injection site of 1 to 7 cm after administration of the vaccine. This swelling will have disappeared or be clearly reduced in size by 14 days post vaccination however in some cases swelling may persist for up to 4 weeks after the second administration.
Common: Mild apathy, anorexia and/or depression may be observed after each injection but these resolve within 4 days.
Very rare: Anaphylactic-type reactions may occur in some sensitive animals. In such cases, appropriate symptomatic treatment such as antihistamines or cortisone or in more severe cases adrenaline should be given..
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment).
- common (more than 1 but less than 10 animals in 100 animals).
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
Use during pregnancy, lactation or lay
Pregnancy:
Do not use during pregnancy.
Lactation:
Do not use during lactation.
Interactions
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Amounts to be administered and administration route
For subcutaneous use.
Cattle: 2 ml / animal.
Recommended vaccination programme:
Administer one dose (2 ml) per calf, at 2 months of age. This 2 ml dose should be repeated after 21 days. Vaccinate calves by subcutaneous injection in the prescapular area. It is preferable to administer the second dose on alternate sides.
The vaccine should be allowed to warm to a temperature between 15 - 20°C before administration. Shake before use. Avoid the introduction of contamination during use. Use only sterile needles and syringes for administration.
Vaccination is recommended to be used before stress periods (shipping, allotments…). The vaccination scheme should be completed 3 weeks before such periods. Protection has not been demonstrated if vaccination scheme is completed earlier than 3 weeks before stress periods.
Overdose (symptoms, emergency procedures, antidotes), if necessary
No effects other than those mentioned above were observed after administration of twice the recommended dose.
Withdrawal periods
Zero Days