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Pharmacological particulars
Summary presentation of the active ingredient.
Fipronil is an insecticide and acaricide from the phenylpyrazole family. It acts by inhibiting the GABA complex, binding to the chloride channel and thereby blocking pre- and post-synaptic transfer of chloride ions across the membrane. This results in uncontrolled activity of the central nervous system and death in insects and acarids.
ATCvet code: QP53AX15
Pharmacodynamic properties
Fipronil exhibits insecticidal and acaricidal activity against fleas (Ctenocephalides spp.), ticks (Rhipicephalus spp. Ixodes spp.) and lice (Trichodectes spp. and Felicola spp.) in the dog and cat.
Fipronil is a member of the phenylpyrazole family of broad spectrum, non-systemic, insecticides/acaricides, which acts by blocking the GABA receptor to kill the target parasite on contact. The product may aid in the control of a number of ectoparasite species in dogs and cats, including Neotrombicula autumnalis, Sarcoptes spp. and Cheyletiella spp.
Treatment with the product has been shown to result in a significant reduction in the incidence of flea allergy dermatitis in both dogs and cats. When used as part of a strategy for the treatment of flea allergy dermatitis, monthly applications to the allergic patient and to other cats and dogs in the household are recommended.