Cattle, sheep, horses and other equines.
Indications for use
A broad-spectrum anthelmintic for the treatment of cattle and sheep infected with mature and developing immature forms of nematodes of the gastro-intestinal and respiratory tracts.
For the treatment of cattle infected with:
The product is usually effective against inhibited larvae of Ostertagia spp. and against Moniezia spp. of tapeworm.
For the treatment of sheep infected with benzimidazole susceptible:
The product is usually effective against Moniezia spp. of tapeworm and may have useful but variable efficacy against Trichuris spp.
For the treatment and control of adult and immature roundworms of the gastro-intestinal tract in horses and other equines.
The product effectively treats and controls the following roundworm infections:
Large strongyles (adults and migrating larval stages of Strongylus vulgaris; adults and tissue larval stages of S. edentatus).
Benzimidazole-susceptible adult and immature small strongyles (Cyathostomes).
The product is also effective for the treatment and control of encysted mucosal 3rd and 4th stage small strongyle larvae and is also effective against encysted inhibited 3rd stage small strongyle larvae in the mucosa.
Adult and immature Oxyuris spp., Strongyloides spp. and Parascaris equorum.
Fenbendazole also has an ovicidal effect on nematode eggs.
Do not use in horses and other equines intended for human consumption.
Fenbendazole as a medicated liquid feed should not be used in the treatment of clinical infestations in cattle and sheep.
Special warnings for each target species
When administered by divided dosage in the form of liquid feed, the product may not be effective against Strongyloides and Trichuris spp. in cattle and Strongyloides, Dictyocaulus and Bunostomum spp. in sheep.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
•Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
•Under dosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to benzimidazoles (which include fenbendazole) has been reported in Teladorsagia, Haemonchus, Cooperia and Trichostrongylus species in small ruminants in a number of countries, including the EU. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Resistance to fenbendazole has been reported in cyathostomes in horses. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use
When incorporating this product into liquid feed, after thoroughly shaking the suspension, measure the required volume of the suspension and add it to approximately 10 % of the liquid feed. Thoroughly mix this material and then add the remaining liquid feed and once again mix to produce a homogenous dispersion.
Mix the medicated feed thoroughly prior to administration for example by rolling the drum or barrel.
Assess body weight as accurately as possible before calculating the dosage.
Intensive use or misuse of anthelmintic can give rise to resistance. To reduce this risk, dosing programmes should be discussed with your veterinary surgeon.
Direct contact with the skin should be kept to a minimum. Wear suitable protective clothing including impermeable rubber gloves.
Wash hands after use.
Use during pregnancy or lactation
The product can be administered to pregnant animals. Pregnant mares and young foals may also be safely treated with fenbendazole at the therapeutic dosage levels.
Amounts to be administered and administration route
Shake container before use. For oral administration only.
No dietary control is required before or after treatment.
To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Cattle and Horses: Administer orally 1 ml of the product per 13 kg body weight. (= 7.5 mg fenbendazole/kg body weight)
Practical dosage recommendations:
Above 400 kg, an extra 3.75 ml are required for each additional 50 kg body weight.
Sheep: Administer orally 0.5 ml per 10 kg body weight (= 5 mg fenbendazole/kg body weight)
Practical dosage recommendations:
Up to 10 kg
11 to 20 kg
21 to 30 kg
31 to 40 kg
41 to 50 kg
51 to 60 kg
61 to 70 kg
71 to 80 kg
Above 80 kg, an extra 0.5 ml is required for each additional 10 kg body weight.
The product is best administered to cattle with the Panacur 20 ml Automatic Drencher and to sheep with the 5ml Sheep Drencher, but other standard dosing guns or drenching equipment may also be used.
For administration to horses, thoroughly mix the product with grain or concentrate feed and give the full dosage as one administration.
Treatment should be repeated when natural re-infection of animals with parasitic worms occurs.
Horses: Recommended dosage programme.
All horses should be routinely wormed with the single dose regimen every 6-8 weeks.
Treatment of encysted inhibited and encysted mucosal dwelling larvae should be performed in the autumn (ideally late October/November) and again in the Spring (ideally in February). However, for horses who fail to maintain condition or bought-in horses with unknown worming history, the treatment can be given at any time of the year.
Five day course
For the treatment and control of migrating and tissue larval stages of large strongyles, encysted mucosal 3rd and 4th stage small strongyle larvae and encysted inhibited 3rd stage small strongyle larvae in the mucosa administer 5 ml of the product per 64 kg body weight daily for 5 days (= 7.5 mg fenbendazole/kg body weight daily for 5 days).
Single dose treatment
For the treatment and control of encysted mucosal stages of small strongyles administer 3 ml of the product per 10 kg body weight (= 30 mg fenbendazole / kg body weight).
For the treatment and control of migrating and tissue stages of large strongyles administer 6 ml of the product per 10 kg body weight (= 60 mg fenbendazole / kg body weight).
For the treatment of diarrhoea cause by Strongyloides westeri in two to three week old sucking foals administer 5 ml of the product per 10kg body weight (= 50mg fenbendazole / kg body weight).
Do not mix with other products.
Benzimidazoles have a high margin of safety. No specific overdose symptoms are known. No specific actions required.
Cattle – Meat: 12 Days
Milk: 5 Days
Sheep - Meat: 15 Days
Milk: 7 Days
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.