Target species
Pigs (sows and gilts).
Indications for use
For the passive immunisation of progeny by active immunisation of sows and gilts to reduce mortality and clinical signs during the first days of life, caused by those E. coli strains, which express the adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6 (987P) and caused by C. perfringens type C.
Contraindications
None.
Special warnings for each target species
Vaccinate healthy animals only
Special precautions for use
Protection of piglets is achieved by colostrum intake. Therefore, care should be taken to ensure that each piglet ingests a sufficient quantity of colostrum.
Operator warnings
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Adverse reactions
Pigs (sows and gilts).
Very Common (> 1 animal / 10 animals treated): | Elevated temperature1, Injection site swelling2. |
Common (1 to 10 animals in 100 animals): | Decreased activity3, Appetite loss3. |
Very rare (< 1 animal / 10,000 animals treated, including isolated reports): | |
1. Up to 2 °C on the day of vaccination.
2. Sometimes painful and hard up to 10 cm in diameter for up to 25 days.
3. On the day of vaccination.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See also section “Contact details” of the package leaflet.
Use during pregnancy or lactation
Can be used during pregnancy.
Interactions
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Amounts to be administered and administration route
Intramuscular use.
Administer 1 dose (2 ml) of vaccine per animal in the neck in the area behind the ear.
Before use, allow the vaccine to reach room temperature.
Shake vigorously before use and at intervals during use.
Vaccination scheme:
Primary vaccination: Sows/gilts which have not yet been vaccinated with the product are given a primary injection 6 to 8 weeks before the expected date of farrowing and a second injection 4 weeks later.
Revaccination: A single revaccination is carried out 2 to 4 weeks before the expected date of farrowing.
Overdose
A slight redness and/or roughness may transiently occur after a double dose vaccination. No adverse reactions other than those mentioned in section “Adverse reactions” have been observed.
Withdrawal period
Zero days.