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Pharmacological particulars
ATCvet code: QP53AC11.
Pharmacotherapeutic group
Ectoparasiticides, insecticides and repellents, pyrethrins and pyrethroids.
Pharmacodynamic properties
Insects and acarines are exposed to deltamethrin through contact. The mechanism of action is based on a sustained increase in the sodium permeability of the insect's nerve membranes. This results in hyperactivity followed by paralysis (shock effect), tremor and death of the parasite.
Pharmacokinetic properties
Deltramethrin is continuously released from the collar into the coat and the fatty film covering the skin. The active substance spreads from the site of direct contact over the entire skin surface through the lipids and in the hair. Deltamethrin is not absorbed systemically by the host.
Environmental properties
Deltamethrin is harmful to fish and other aquatic organisms.