For the active immunisation of sheep and cattle against diseases associated with infections caused by Clostridium perfringens type A, C.perfringens type B, C.perfringens type C, C.perfringens type D, Clostridium chauvoei, Clostridium novyi type B, Clostridium septicum, Clostridium sordellii and Clostridium haemolyticum and against tetanus caused by Clostridium tetani.
For the passive immunisation of lambs and calves against infections caused by the above mentioned clostridial species (except C.haemolyticum in sheep).
Onset of immunity: 2 weeks after the basic vaccination course (as demonstrated by serology only).
Duration of active immunity as demonstrated by serology only:
Sheep: 12 months against C. perfringens type A, B, C, and D, C. novyi type B, C. sordellii, C. tetani
< 6 months against C. septicum, C. haemolyticum, C. chauvoei
Cattle: 12 months against C. tetani and C. perfringens type D
< 12 months against C. perfringens type A, B and C
< 6 months against C. novyi type B, C. septicum, C. sordellii, C. haemolyticum, C.chauvoei
Additionally, an anamnestic humoral immune response (immunological memory) to all components was demonstrated after antigen stimulation 12 months after the basic vaccination course.
Duration of passive immunity as demonstrated by serology titre only:
Lambs: At least 2 weeks for C. septicum and C. chauvoei, at least 8 weeks for C. perfringens type B and C. perfringens type C and at least 12 weeks for C. perfringens type A, C. perfringens type D, C. novyi type B, C. tetani and C. sordellii. No passive immunity was observed for C. haemoloyticum.
Calves: At least 2 weeks for C. sordellii, and C. haemolyticum, at least 8 weeks for C. septicum and C. chauvoei and at least 12 weeks for C. perfringens type A, C. perfringens type B, C. perfringens type C, C. perfringens type D, C. novyi type B, and C. tetani.