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Date: Saturday, May 18, 2024 22:03

Description: Zoetis logo
Release 3.23
Dermisol Cream
Species: Horses and other equidae, Cats, Cattle, Dogs
Therapeutic indication: Pharmaceuticals: Antiseptics: Udder washes and creams, General/other antiseptics
Active ingredient: Propylene Glycol, Salicylic Acid
Product:Dermisol® Cream
Product index: Dermisol Cream
Cattle - milk: Zero hours
Cattle - meat: Zero days
Withdrawal notes: Horses: Zero days
Dermisol Cream is a white cream for topical application. The product is prepared from the following active ingredients:
Propylene Glycol
1.750% v/v
Malic acid
0.375% w/v
Benzoic Acid
0.025% w/v
Salicylic Acid
0.006% w/v
Dermisol Cream may be used to encourage healing in horses, cattle, dogs and cats particularly when this process is impaired by the presence of necrotic tissue, coagulum, debris or wax. This may occur in cases of traumatic injury, surgical wounds, infected wounds and otitis externa.
Dermisol Cream aids healing by removing dead and necrotic tissue from affected areas.
This is achieved by differential swelling of necrotic and healthy tissues leading to separation of the devitalised areas and embedded debris.
Dosage and administration
Dermisol Cream is for topical use only. Dermisol Cream should be applied twice daily although more frequent applications may be made if necessary.
Wounds: The cream should be spread liberally on to wound surfaces and before each new application it is advisable to wash the area with a multicleansing solution so that loose slough and cream from the previous application are removed without raising the pH.
Otitis externa: In cases of otitis externa, ears should be cleaned with a multicleansing solution prior to the introduction of Dermisol Cream into the external auditory canal.
Contra-indications, warnings, etc
For external use only. For topical use only.
Care should be taken to avoid contact with the eyes because of the low pH and a possible irritant effect. If contact occurs, rinse with clean, fresh water. May cause skin irritation. It is recommended that gloves be worn when handling the product if you have sensitive skin. Wash hands after use.
When used for treating udder lesions in cattle, the udder and the teats should be washed immediately before the next milking.
Do not use in conjunction with other products, e.g. teat dips, udder disinfectants, etc. as these will almost certainly neutralise and reduce the effectiveness of Dermisol.
Do not use in the treatment of otitis externa in animals with a ruptured ear drum.
Withdrawal periods
meat - zero days.
milk - zero hours.
meat - zero days.
Pharmaceutical precautions
Do not store above 25°C.
Prolonged contact with metal surfaces is inadvisable.
Keep out of the sight and reach of children. For animal treatment only. Dispose of empty packaging and any remaining product in the household or farm refuse.
Legal category
Legal category: POM-VPS
Packaging quantities
Dermisol Cream is available in 30 g and 100 g tubes. Not all pack sizes may be marketed.
Further information
Dermisol aids the removal of dead tissue and any embedded debris by causing maximum differential swelling between live and dead areas.
This is achieved in two ways:
1The low pH causes separation of collagen molecules by rupturing the hydrogen bonding. The optimum pH to achieve this effect is between pH 2 and pH 3.
2The organic acid reacts with carboxyl and amino groups in the collagen. The insertion of the organic acid forces the collagen chains apart.
In both cases the devitalised tissues absorb water and swell markedly.
Healthy tissue is unaffected because of natural barriers to organic acids and sufficient buffering capacity to maintain a near neutral pH.
Marketing Authorisation Number
Vm 42058/4035
Significant changes
GTIN description:30 g:
GTIN description:100 g: