Do not administer to young foals less than 6.5 months of age.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Equest Pramox Oral Gel is formulated specifically for use in horses only. Dogs or cats may be adversely affected by the concentration of moxidectin in this product if they are allowed to ingest spilled gel or have access to used syringes.
Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other on the same premises.
Meat and offal: 64 days.
Milk: not permitted for use in lactating mares producing milk for human consumption.
This product may cause eye irritation, skin irritation and skin sensitisation.
Avoid direct contact with skin and eyes.
The use of protective gloves is recommended.
Wash hands or any exposed area after use.
Do not smoke, drink or eat while handling the product.
In the event of eye contact flush the eye with copious amounts of clean water and seek medical advice.
In case of accidental ingestion, seek medical help and show the doctor the package insert.
Other precautions regarding impact on the environment
Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited to the extent possible. Treatments should be administered only when necessary and should be based on faecal egg counts or evaluation of the risk of infestation at the animal and/or herd level. In order to reduce the emission of moxidectin to surface water and based on the excretion profile of moxidectin when administered as the oral formulation to horses, treated animals should not have access to watercourses during the first week after treatment.
Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-target organisms:
•Faeces containing moxidectin excreted onto pasture by treated animals may temporarily reduce the abundance of dung feeding organisms. Following treatment of horses with the product, levels of moxidectin that are potentially toxic to dung beetles and flies may be excreted over a period of more than 1 week and may decrease dung fauna abundance.
•Moxidectin is inherently toxic to aquatic organisms including fish. The product should be used only according to the label instructions.