The use of Excenel Sterile Powder is contra-indicated in animals previously found to be hypersensitive to ceftiofur.
Do not use in poultry (including eggs) due to the risk of spread of antimicrobial resistance to humans.
The use of the product may cause occasional local discomfort upon injection but this is a transient effect.
The administration of antimicrobials to horses under conditions of stress may be associated with acute diarrhoea which could be fatal. If acute diarrhoea is observed, discontinue use of this antimicrobial and initiate appropriate therapy.
Excenel Sterile Powder selects for resistant strains such as bacteria carrying extended spectrum betalactamases (ESBL) and may constitute a risk to human health if these strains disseminate to humans e.g. via food. For this reason, Excenel Sterile Powder should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly (refers to very acute cases when treatment must be initiated without bacteriological diagnosis) to first line treatment.
Official, national and regional antimicrobial policies should be taken into account when the product is used. Increased use, including use of the product deviating from the instructions given in the SPC, may increase the prevalence of such resistance. Whenever possible, Excenel Sterile Powder should only be used based on susceptibility testing.
Excenel Sterile Powder is intended for treatment of individual animals. Do not use for disease prevention or as a part of herd health programmes. Treatment of groups of animals should be strictly restricted to ongoing disease outbreaks according to the approved conditions of use.
Withdrawal period
Cattle: meat: 1 day.
Milk: zero hours.
Pigs: meat: 2 days.
Horses: Not for use in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
Operator warnings
Care should be taken to avoid accidental self-injection. In the event of accidental self-injection, seek medical advice immediately.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Handle this product with great care to avoid exposure taking all recommended precautions.
If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.
Wash hands after use.