Vaccinate healthy animals only.
Do not vaccinate animals undergoing antibacterial or immunosuppressive treatment.
Special warnings
Do not use antibiotic treatment within 1 week before and after vaccination because antibiotic treatment might impair the efficacy of the vaccine.
No information is available on the influence of high levels of maternally derived antibodies on the efficacy.
The vaccine strain can be detected in tissues (liver, heart) until 6 days (chickens) or in tissues (thoracic air sacs) until 4 days (turkeys) post vaccination. Vaccinated birds may excrete the vaccine strain by faecal route for up to 5 weeks (chickens) or 7 days (turkeys) post vaccination, and the vaccine may remain present in the environment until the end of the finishing or rearing period (chickens) or for 7 days (turkeys). Therefore, it is recommended to clean and disinfect bird houses where the vaccine was applied after completion of the finishing or rearing period.
The vaccine strain may spread to in-contact birds.
The vaccine strain can be identified by its growth properties on biological growth media: it shows normal growth on MacConkey and trypticase soy agar, while no colonies are observed when plated without aromatic amino acids (minimum agar).
Immunisation has to be considered as one component in a complex control program that addresses all important hygienic and health factors for poultry.
The safety of Poulvac E. coli has been demonstrated when administered to chickens during lay. The efficacy of Poulvac E. coli has not been demonstrated when administered to chickens during lay. A decision to use this vaccine in chickens during lay should be made on a case by case basis.
The safety of Poulvac E. coli has not been investigated in turkeys during lay. Do not use in turkeys in lay and within 6 weeks before the start of the laying period.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Do not mix with any other veterinary medicinal product.
Withdrawal period
Zero days.
Operator warnings
Apply the usual aseptic precautions to all administration procedures.
The use of eye-protection, gloves and a nose-mouth mask by the operator is advised during administration. Immunosuppressed people should not be present during administration of the vaccine. Disinfect hands and equipment after use.
Personnel involved in attending vaccinated animals should follow general hygiene principals and take particular care in handling litter from recently vaccinated animals.